The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression.

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Title: The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression.
Authors: Lee CJ; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Yun HJ; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Jang TY; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Jeon SE; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Cho YH; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Lim DY; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Han EJ; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Kong SY; Targeted Therapy Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea.; Cancer Biomedical Science, National Cancer Center, Goyang, Republic of Korea.; Department of Laboratory Medicine, National Cancer Center, Goyang, Republic of Korea., Nam JS; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. namje@gist.ac.kr.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jan 15; Vol. 11 (1), pp. 19. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression.
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  Data: <searchLink fieldCode="AU" term="%22Lee+CJ%22">Lee CJ</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yun+HJ%22">Yun HJ</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jang+TY%22">Jang TY</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+SE%22">Jeon SE</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YH%22">Cho YH</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+DY%22">Lim DY</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+EJ%22">Han EJ</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kong+SY%22">Kong SY</searchLink>; Targeted Therapy Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea.; Cancer Biomedical Science, National Cancer Center, Goyang, Republic of Korea.; Department of Laboratory Medicine, National Cancer Center, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nam+JS%22">Nam JS</searchLink>; Department of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. namje@gist.ac.kr.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1038/s41392-025-02543-x
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        Text: English
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      – TitleFull: The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression.
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              Text: 2026 Jan 15
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