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H3K27me3-dependent imprinting and transcriptional regulation in early mouse embryos requires EZHIP-mediated restriction of PRC2 activity.

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Title: H3K27me3-dependent imprinting and transcriptional regulation in early mouse embryos requires EZHIP-mediated restriction of PRC2 activity.
Authors: Diop S; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Richart L; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Petitalot A; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Boni J; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Mollier C; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Altay B; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Dauphin A; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Raynal V; Institut Curie Genomics of Excellence (ICGex) Platform, Research Center, Institut Curie, Paris, France.; INSERM U1330/CNRS EMR 8001, Childrens' ONCology rEseaRch uniT (CONCERT), Paris, France., Maître JL; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France., Ancelin K; Institut Curie, Paris Sciences et Lettres Research University, Paris, France. katia.ancelin@inserm.fr.; INSERM U934 & CNRS UMR 3215, Paris, France. katia.ancelin@inserm.fr.; Université Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France. katia.ancelin@inserm.fr., Margueron R; Institut Curie, Paris Sciences et Lettres Research University, Paris, France. raphael.margueron@curie.fr.; INSERM U934 & CNRS UMR 3215, Paris, France. raphael.margueron@curie.fr.
Source: Nature communications [Nat Commun] 2026 Jan 15; Vol. 17 (1), pp. 1758. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: H3K27me3-dependent imprinting and transcriptional regulation in early mouse embryos requires EZHIP-mediated restriction of PRC2 activity.
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  Data: <searchLink fieldCode="AU" term="%22Diop+S%22">Diop S</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Richart+L%22">Richart L</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Petitalot+A%22">Petitalot A</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Boni+J%22">Boni J</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mollier+C%22">Mollier C</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Altay+B%22">Altay B</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dauphin+A%22">Dauphin A</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Raynal+V%22">Raynal V</searchLink>; Institut Curie Genomics of Excellence (ICGex) Platform, Research Center, Institut Curie, Paris, France.; INSERM U1330/CNRS EMR 8001, Childrens' ONCology rEseaRch uniT (CONCERT), Paris, France.<br /><searchLink fieldCode="AU" term="%22Maître+JL%22">Maître JL</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France.; INSERM U934 & CNRS UMR 3215, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ancelin+K%22">Ancelin K</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France. katia.ancelin@inserm.fr.; INSERM U934 & CNRS UMR 3215, Paris, France. katia.ancelin@inserm.fr.; Université Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France. katia.ancelin@inserm.fr.<br /><searchLink fieldCode="AU" term="%22Margueron+R%22">Margueron R</searchLink>; Institut Curie, Paris Sciences et Lettres Research University, Paris, France. raphael.margueron@curie.fr.; INSERM U934 & CNRS UMR 3215, Paris, France. raphael.margueron@curie.fr.
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