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In vitro comparative assessment of metabolic stability and structure-metabolism relationships of five fentanyl analogs with varying N-acyl side chain lengths.

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Bibliographic Details
Title: In vitro comparative assessment of metabolic stability and structure-metabolism relationships of five fentanyl analogs with varying N-acyl side chain lengths.
Authors: Murakami T; Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters, Kanazawa, Japan. murakami@forensic-sci-lab.net.; Institute of Science and Engineering, Kanazawa University, Kanazawa, Japan. murakami@forensic-sci-lab.net., Watanabe S; Forensic Science Group, Photon Science Research Division, RIKEN SPring-8 Center, Sayo, Japan., Imamura Y; Forensic Science Laboratory, Mie Prefectural Police Headquarters, Tsu, Japan., Kanda K; Forensic Science Laboratory, Mie Prefectural Police Headquarters, Tsu, Japan., Ishimaru R; Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters, Kanazawa, Japan., Chinaka S; Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters, Kanazawa, Japan.; Institute of Science and Engineering, Kanazawa University, Kanazawa, Japan.; Department of Forensic Medicine and Pathology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
Source: Archives of toxicology [Arch Toxicol] 2026 Apr; Vol. 100 (4), pp. 1515-1526. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0738
DOI:10.1007/s00204-025-04281-z