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Phase I Studies of HLX26, A Novel Anti-LAG-3 Antibody, Monotherapy or Combination Therapy in Patients with Advanced Solid Tumors.

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Title: Phase I Studies of HLX26, A Novel Anti-LAG-3 Antibody, Monotherapy or Combination Therapy in Patients with Advanced Solid Tumors.
Authors: Liu R; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China., Jing H; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China., Chen Y; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China., Gao S; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China., Zhang J; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China., Cao X; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China., Li K; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China., Liu Y; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China., Meng M; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China., Chen C; Shanghai Henlius Biotech, Inc., Shanghai, China., Sun C; Shanghai Henlius Biotech, Inc., Shanghai, China., Yu H; Shanghai Henlius Biotech, Inc., Shanghai, China., Wang Q; Shanghai Henlius Biotech, Inc., Shanghai, China., Li J; Shanghai Henlius Biotech, Inc., Shanghai, China., Wu Y; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China. wymin666@126.com., Zhang J; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China. syner2000@163.com.
Source: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [BioDrugs] 2026 Mar; Vol. 40 (2), pp. 335-348. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9705305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-190X (Electronic) Linking ISSN: 11738804 NLM ISO Abbreviation: BioDrugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase I Studies of HLX26, A Novel Anti-LAG-3 Antibody, Monotherapy or Combination Therapy in Patients with Advanced Solid Tumors.
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  Data: <searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China.<br /><searchLink fieldCode="AU" term="%22Jing+H%22">Jing H</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China.<br /><searchLink fieldCode="AU" term="%22Cao+X%22">Cao X</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China.<br /><searchLink fieldCode="AU" term="%22Li+K%22">Li K</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China.<br /><searchLink fieldCode="AU" term="%22Meng+M%22">Meng M</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Shanghai Henlius Biotech, Inc., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+C%22">Sun C</searchLink>; Shanghai Henlius Biotech, Inc., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Shanghai Henlius Biotech, Inc., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Shanghai Henlius Biotech, Inc., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Shanghai Henlius Biotech, Inc., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Pulmonary and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, 210000, China. wymin666@126.com.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Phase I Clinical Research Center, Fudan University Cancer Hospital, Shanghai, 200000, China. syner2000@163.com.
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  Data: <searchLink fieldCode="JN" term="%229705305%22">BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy</searchLink> [BioDrugs] 2026 Mar; Vol. 40 (2), pp. 335-348. <i>Date of Electronic Publication: </i>2026 Jan 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9705305 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-190X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211738804%22">11738804 </searchLink><i>NLM ISO Abbreviation: </i>BioDrugs <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s40259-025-00751-z
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        Text: English
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        StartPage: 335
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              Text: 2026 Mar
              Type: published
              Y: 2026
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