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Investigating the SNAC-to-drug ratio for the oral absorption of cyanocobalamin in rats.

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Title: Investigating the SNAC-to-drug ratio for the oral absorption of cyanocobalamin in rats.
Authors: Chiang PC; Small Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: chiang.pochang@gene.com., Liu J; Small Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Nagapudi K; Small Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Pang J; Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Plise E; Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Dolton M; Clinical Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Durk MR; Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Source: Journal of pharmaceutical sciences [J Pharm Sci] 2026 Mar; Vol. 115 (3), pp. 104163. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chiang+PC%22">Chiang PC</searchLink>; Small Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: chiang.pochang@gene.com.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Small Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Nagapudi+K%22">Nagapudi K</searchLink>; Small Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Pang+J%22">Pang J</searchLink>; Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Plise+E%22">Plise E</searchLink>; Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Dolton+M%22">Dolton M</searchLink>; Clinical Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Durk+MR%22">Durk MR</searchLink>; Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
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  Data: <searchLink fieldCode="JN" term="%222985195R%22">Journal of pharmaceutical sciences</searchLink> [J Pharm Sci] 2026 Mar; Vol. 115 (3), pp. 104163. <i>Date of Electronic Publication: </i>2026 Jan 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985195R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-6017 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223549%22">00223549 </searchLink><i>NLM ISO Abbreviation: </i>J Pharm Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.xphs.2026.104163
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        Text: English
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      – TitleFull: Investigating the SNAC-to-drug ratio for the oral absorption of cyanocobalamin in rats.
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            NameFull: Chiang PC
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              Text: 2026 Mar
              Type: published
              Y: 2026
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