A novel murine model of LITT for glioblastoma reveals tumor reduction, BBB permeabilization, and drug delivery via ThermoDox®.

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Title: A novel murine model of LITT for glioblastoma reveals tumor reduction, BBB permeabilization, and drug delivery via ThermoDox®.
Authors: Athukuri P; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Moreno K; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., McDonald MF; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Puentes A; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Dei-Ampeh A; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Marisetty A; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Yang Y; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Lee S; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Latha K; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Needham D; Department of Mechanical Engineering and Materials Science, School of Engineering, Duke University, Durham, NC, 27708-0300, USA.; School of Pharmacy, University of Nottingham, Nottingham, UK.; DNKO LLC (DNKO for Brain Cancer), Apple Valley, CA, USA., Rao G; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA. grao@bcm.edu.
Source: Drug delivery and translational research [Drug Deliv Transl Res] 2026 Jan 15. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel murine model of LITT for glioblastoma reveals tumor reduction, BBB permeabilization, and drug delivery via ThermoDox<superscript>®</superscript>.
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  Data: <searchLink fieldCode="AU" term="%22Athukuri+P%22">Athukuri P</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Moreno+K%22">Moreno K</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22McDonald+MF%22">McDonald MF</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Puentes+A%22">Puentes A</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dei-Ampeh+A%22">Dei-Ampeh A</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Marisetty+A%22">Marisetty A</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Latha+K%22">Latha K</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Needham+D%22">Needham D</searchLink>; Department of Mechanical Engineering and Materials Science, School of Engineering, Duke University, Durham, NC, 27708-0300, USA.; School of Pharmacy, University of Nottingham, Nottingham, UK.; DNKO LLC (DNKO for Brain Cancer), Apple Valley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rao+G%22">Rao G</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA. grao@bcm.edu.
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  Data: <searchLink fieldCode="JN" term="%22101540061%22">Drug delivery and translational research</searchLink> [Drug Deliv Transl Res] 2026 Jan 15. <i>Date of Electronic Publication: </i>2026 Jan 15.
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        Value: 10.1007/s13346-025-02035-z
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        Text: English
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      – TitleFull: A novel murine model of LITT for glioblastoma reveals tumor reduction, BBB permeabilization, and drug delivery via ThermoDox®.
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              Text: 2026 Jan 15
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