1-deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway.

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Bibliographic Details
Title: 1-deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway.
Authors: Tsai YT; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA., Lipp NF; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA., Seidel O; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA., Varma R; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA., Laguerre A; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Salk Institute of Biological Studies, La Jolla, CA 92037, USA., Solorio-Kirpichyan K; Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA., Wong AM; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA., Brea RJ; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA; CICA - Centro Interdisciplinar de Química e Bioloxía e Departamento de Química, Facultade de Ciencias, Universidade da Coruña, Rúa As Carballeiras, 15701 A Coruña, Spain., McGregor GH; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Salk Institute of Biological Studies, La Jolla, CA 92037, USA., Cordes T; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Salk Institute of Biological Studies, La Jolla, CA 92037, USA., Devaraj NK; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA., Kuerschner L; Life & Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany., Neal S; Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA., Metallo CM; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Salk Institute of Biological Studies, La Jolla, CA 92037, USA., Budin I; Department of Biochemistry & Molecular Biophysics, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: ibudin@ucsd.edu.
Source: Cell chemical biology [Cell Chem Biol] 2026 Jan 15; Vol. 33 (1), pp. 45-58.e8.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2451-9448
DOI:10.1016/j.chembiol.2025.12.006