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Low-dose yellow fever vaccination in infants: a randomised, double-blind, non-inferiority trial.

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Title: Low-dose yellow fever vaccination in infants: a randomised, double-blind, non-inferiority trial.
Authors: Kimathi D; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Juan-Giner A; Epicentre, Paris, France., Bob NS; Institut Pasteur de Dakar, Dakar, Senegal., Orindi B; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Namulwana ML; Epicentre Mbarara Research Centre, Mbarara, Uganda., Diatta A; Institut Pasteur de Dakar, Dakar, Senegal., Cheruiyot S; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Fall G; Institut Pasteur de Dakar, Dakar, Senegal., Dia M; Institut Pasteur de Dakar, Dakar, Senegal., Hamaluba MM; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Nyehangane D; Epicentre Mbarara Research Centre, Mbarara, Uganda., Karanja HK; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Gitonga JN; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Mugo D; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Omuoyo DO; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Hussein M; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Oloo E; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Kamau N; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Wafula J; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Bendera J; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Silvester N; Epicentre Mbarara Research Centre, Mbarara, Uganda., Mwavita J; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Joshua M; Epicentre Mbarara Research Centre, Mbarara, Uganda., Thuranira JM; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Agababyona C; Epicentre Mbarara Research Centre, Mbarara, Uganda., Ngetsa C; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Aisha N; Epicentre Mbarara Research Centre, Mbarara, Uganda., Moki F; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Buluku T; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Munene M; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya., Mwanga-Amumpaire J; Epicentre Mbarara Research Centre, Mbarara, Uganda., Lutwama J; Uganda Virus Research Institute, Entebbe, Uganda., Kayiwa J; Uganda Virus Research Institute, Entebbe, Uganda., Kamaara E; Moi University, Eldoret, Kenya., Barrett AD; Sealy Institute for Vaccines Sciences and Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA., Kaleebu P; Uganda Virus Research Institute, Entebbe, Uganda; Medical Research Council-Uganda Virus Research Institute and The London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Bejon P; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sall AA; Institut Pasteur de Dakar, Dakar, Senegal., Grais RF; Epicentre, Paris, France., Warimwe GM; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: gwarimwe@kemri-wellcome.org.
Source: Lancet (London, England) [Lancet] 2026 Jan 31; Vol. 407 (10527), pp. 497-504. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Equivalence Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Low-dose yellow fever vaccination in infants: a randomised, double-blind, non-inferiority trial.
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  Data: <searchLink fieldCode="AU" term="%22Kimathi+D%22">Kimathi D</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Juan-Giner+A%22">Juan-Giner A</searchLink>; Epicentre, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bob+NS%22">Bob NS</searchLink>; Institut Pasteur de Dakar, Dakar, Senegal.<br /><searchLink fieldCode="AU" term="%22Orindi+B%22">Orindi B</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Namulwana+ML%22">Namulwana ML</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Diatta+A%22">Diatta A</searchLink>; Institut Pasteur de Dakar, Dakar, Senegal.<br /><searchLink fieldCode="AU" term="%22Cheruiyot+S%22">Cheruiyot S</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Fall+G%22">Fall G</searchLink>; Institut Pasteur de Dakar, Dakar, Senegal.<br /><searchLink fieldCode="AU" term="%22Dia+M%22">Dia M</searchLink>; Institut Pasteur de Dakar, Dakar, Senegal.<br /><searchLink fieldCode="AU" term="%22Hamaluba+MM%22">Hamaluba MM</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Nyehangane+D%22">Nyehangane D</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Karanja+HK%22">Karanja HK</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Gitonga+JN%22">Gitonga JN</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Mugo+D%22">Mugo D</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Omuoyo+DO%22">Omuoyo DO</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Hussein+M%22">Hussein M</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Oloo+E%22">Oloo E</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Kamau+N%22">Kamau N</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Wafula+J%22">Wafula J</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Bendera+J%22">Bendera J</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Silvester+N%22">Silvester N</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Mwavita+J%22">Mwavita J</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Joshua+M%22">Joshua M</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Thuranira+JM%22">Thuranira JM</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Agababyona+C%22">Agababyona C</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Ngetsa+C%22">Ngetsa C</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Aisha+N%22">Aisha N</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Moki+F%22">Moki F</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Buluku+T%22">Buluku T</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Munene+M%22">Munene M</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.<br /><searchLink fieldCode="AU" term="%22Mwanga-Amumpaire+J%22">Mwanga-Amumpaire J</searchLink>; Epicentre Mbarara Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Lutwama+J%22">Lutwama J</searchLink>; Uganda Virus Research Institute, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kayiwa+J%22">Kayiwa J</searchLink>; Uganda Virus Research Institute, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kamaara+E%22">Kamaara E</searchLink>; Moi University, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Barrett+AD%22">Barrett AD</searchLink>; Sealy Institute for Vaccines Sciences and Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kaleebu+P%22">Kaleebu P</searchLink>; Uganda Virus Research Institute, Entebbe, Uganda; Medical Research Council-Uganda Virus Research Institute and The London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Bejon+P%22">Bejon P</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sall+AA%22">Sall AA</searchLink>; Institut Pasteur de Dakar, Dakar, Senegal.<br /><searchLink fieldCode="AU" term="%22Grais+RF%22">Grais RF</searchLink>; Epicentre, Paris, France.<br /><searchLink fieldCode="AU" term="%22Warimwe+GM%22">Warimwe GM</searchLink>; Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: gwarimwe@kemri-wellcome.org.
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  Data: <searchLink fieldCode="JN" term="%222985213R%22">Lancet (London, England)</searchLink> [Lancet] 2026 Jan 31; Vol. 407 (10527), pp. 497-504. <i>Date of Electronic Publication: </i>2026 Jan 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985213R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-547X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201406736%22">01406736 </searchLink><i>NLM ISO Abbreviation: </i>Lancet <i>Subsets: </i>MEDLINE
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