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Assessing the effectiveness of a depression-integrated model in adult HIV care in Uganda (the HIV+D trial): a cluster-randomised controlled trial.

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Title: Assessing the effectiveness of a depression-integrated model in adult HIV care in Uganda (the HIV+D trial): a cluster-randomised controlled trial.
Authors: Kinyanda E; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda; Department of Psychiatry, Makerere University, College of Health Science, New Mulago Hill, Kampala, Uganda. Electronic address: eugene.kinyanda@mrcuganda.org., Kyohangirwe L; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Mpango RS; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Sekitoleko I; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Ssembajjwe W; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Tusiime C; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Ssebunnya J; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Katumba K; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Kiconco BE; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Laurence Y; Faculty of Life Sciences & Medicine, King's College London, London, UK., Tenya P; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Turyahabwa J; Human Resource Department, Makerere University Business School, Kampala, Uganda., Katana P; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK., Ross I; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK., Vassall A; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK., Greco G; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK., Mugisha J; Faculty of Social Sciences, Kyambogo University, Kampala, Uganda., Taasi G; HIV Testing Services, Ministry of Health, Uganda, Kampala, Uganda., Sentongo H; Mental Health and Control of Substance Abuse, Ministry of Health, Uganda, Kampala, Uganda., Akena D; Department of Psychiatry, Makerere University, College of Health Science, New Mulago Hill, Kampala, Uganda., Muhwezi WW; Department of Psychiatry, Makerere University, College of Health Science, New Mulago Hill, Kampala, Uganda., Weiss HA; MRC International Statistics & Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK., Neuman M; MRC International Statistics & Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK., Knizek BL; Department of Mental Health, Norwegian University of Science and Technology, Campus Øya, Trondheim, Norway., Levin J; School of Public Health, University of the Witwatersrand, Johannesburg, South Africa., Kaleebu P; Pathogen Genomics Phenotype and Immunity, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda., Araya R; Centre for Global Mental Health, King's College London, David Goldberg Centre, London, UK., Patel V; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Source: The lancet. HIV [Lancet HIV] 2026 Feb; Vol. 13 (2), pp. e104-e115. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101645355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3018 (Electronic) Linking ISSN: 23523018 NLM ISO Abbreviation: Lancet HIV Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Assessing the effectiveness of a depression-integrated model in adult HIV care in Uganda (the HIV+D trial): a cluster-randomised controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Kinyanda+E%22">Kinyanda E</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda; Department of Psychiatry, Makerere University, College of Health Science, New Mulago Hill, Kampala, Uganda. Electronic address: eugene.kinyanda@mrcuganda.org.<br /><searchLink fieldCode="AU" term="%22Kyohangirwe+L%22">Kyohangirwe L</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Mpango+RS%22">Mpango RS</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Sekitoleko+I%22">Sekitoleko I</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Ssembajjwe+W%22">Ssembajjwe W</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Tusiime+C%22">Tusiime C</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Ssebunnya+J%22">Ssebunnya J</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Katumba+K%22">Katumba K</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kiconco+BE%22">Kiconco BE</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Laurence+Y%22">Laurence Y</searchLink>; Faculty of Life Sciences & Medicine, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Tenya+P%22">Tenya P</searchLink>; Mental Health Focus Area, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Turyahabwa+J%22">Turyahabwa J</searchLink>; Human Resource Department, Makerere University Business School, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Katana+P%22">Katana P</searchLink>; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Ross+I%22">Ross I</searchLink>; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Vassall+A%22">Vassall A</searchLink>; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Greco+G%22">Greco G</searchLink>; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Mugisha+J%22">Mugisha J</searchLink>; Faculty of Social Sciences, Kyambogo University, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Taasi+G%22">Taasi G</searchLink>; HIV Testing Services, Ministry of Health, Uganda, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Sentongo+H%22">Sentongo H</searchLink>; Mental Health and Control of Substance Abuse, Ministry of Health, Uganda, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Akena+D%22">Akena D</searchLink>; Department of Psychiatry, Makerere University, College of Health Science, New Mulago Hill, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Muhwezi+WW%22">Muhwezi WW</searchLink>; Department of Psychiatry, Makerere University, College of Health Science, New Mulago Hill, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Weiss+HA%22">Weiss HA</searchLink>; MRC International Statistics & Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Neuman+M%22">Neuman M</searchLink>; MRC International Statistics & Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Knizek+BL%22">Knizek BL</searchLink>; Department of Mental Health, Norwegian University of Science and Technology, Campus Øya, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Levin+J%22">Levin J</searchLink>; School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Kaleebu+P%22">Kaleebu P</searchLink>; Pathogen Genomics Phenotype and Immunity, Medical Research Council, Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Araya+R%22">Araya R</searchLink>; Centre for Global Mental Health, King's College London, David Goldberg Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Patel+V%22">Patel V</searchLink>; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101645355%22">The lancet. HIV</searchLink> [Lancet HIV] 2026 Feb; Vol. 13 (2), pp. e104-e115. <i>Date of Electronic Publication: </i>2026 Jan 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101645355 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-3018 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223523018%22">23523018 </searchLink><i>NLM ISO Abbreviation: </i>Lancet HIV <i>Subsets: </i>MEDLINE
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