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A Prospective Multicenter Observational Study Investigating the Concordance Between Patient-Reported Hearing Loss and Commonly Used Ototoxicity Grading Systems in Patients Treated with Platinum-Based Chemotherapy.

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Title: A Prospective Multicenter Observational Study Investigating the Concordance Between Patient-Reported Hearing Loss and Commonly Used Ototoxicity Grading Systems in Patients Treated with Platinum-Based Chemotherapy.
Authors: Burger AVM; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands., Duinkerken CW; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.; Department of Otolaryngology, Haaglanden Medical Center, The Hague, The Netherlands., Theunissen EAR; Department of Otolaryngology, Reinier de Graaf Hospital, Delft, The Netherlands., Schaeffers AWMA; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands., Hauptmann M; Institute of Biostatistics and Registry Research, Brandenburg Medical School Theodor Fontane, Neuruppin, Germany., Hoetink AE; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands., Balm AJM; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., de Boer JP; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Maas-Bannink E; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Exterkate L; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Slingerland M; Department of Medical Oncology, Leiden University Medical Center, Leiden University, The Netherlands., Jansen JC; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands., Stokroos RJ; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands., de Bree R; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands., Devriese LA; Department of Medical Oncology, University Medical Center Utrecht, The Netherlands., Dreschler WA; Department of Audiology, Amsterdam University Medical Center, The Netherlands., Bruintjes TD; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.; Apeldoorn Dizziness Centre, Gelre Hospital Apeldoorn, The Netherlands., van Sluis KE; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Zuur CL; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.
Source: The Annals of otology, rhinology, and laryngology [Ann Otol Rhinol Laryngol] 2026 Jun; Vol. 135 (6), pp. 443-452. Date of Electronic Publication: 2026 Jan 18.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: Sage Country of Publication: United States NLM ID: 0407300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-572X (Electronic) Linking ISSN: 00034894 NLM ISO Abbreviation: Ann Otol Rhinol Laryngol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Prospective Multicenter Observational Study Investigating the Concordance Between Patient-Reported Hearing Loss and Commonly Used Ototoxicity Grading Systems in Patients Treated with Platinum-Based Chemotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Burger+AVM%22">Burger AVM</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Duinkerken+CW%22">Duinkerken CW</searchLink>; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.; Department of Otolaryngology, Haaglanden Medical Center, The Hague, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Theunissen+EAR%22">Theunissen EAR</searchLink>; Department of Otolaryngology, Reinier de Graaf Hospital, Delft, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schaeffers+AWMA%22">Schaeffers AWMA</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hauptmann+M%22">Hauptmann M</searchLink>; Institute of Biostatistics and Registry Research, Brandenburg Medical School Theodor Fontane, Neuruppin, Germany.<br /><searchLink fieldCode="AU" term="%22Hoetink+AE%22">Hoetink AE</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Balm+AJM%22">Balm AJM</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Boer+JP%22">de Boer JP</searchLink>; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Maas-Bannink+E%22">Maas-Bannink E</searchLink>; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Exterkate+L%22">Exterkate L</searchLink>; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Slingerland+M%22">Slingerland M</searchLink>; Department of Medical Oncology, Leiden University Medical Center, Leiden University, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jansen+JC%22">Jansen JC</searchLink>; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stokroos+RJ%22">Stokroos RJ</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Bree+R%22">de Bree R</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, UMC Brain Centre, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Devriese+LA%22">Devriese LA</searchLink>; Department of Medical Oncology, University Medical Center Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dreschler+WA%22">Dreschler WA</searchLink>; Department of Audiology, Amsterdam University Medical Center, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bruintjes+TD%22">Bruintjes TD</searchLink>; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.; Apeldoorn Dizziness Centre, Gelre Hospital Apeldoorn, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Sluis+KE%22">van Sluis KE</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zuur+CL%22">Zuur CL</searchLink>; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden University, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%220407300%22">The Annals of otology, rhinology, and laryngology</searchLink> [Ann Otol Rhinol Laryngol] 2026 Jun; Vol. 135 (6), pp. 443-452. <i>Date of Electronic Publication: </i>2026 Jan 18.
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