Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson's disease.

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Title: Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson's disease.
Authors: Huang Y; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Wen H; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Li L; XellSmart Biopharmaceutical (Suzhou) Co., Ltd, Suzhou, China., Li L; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Li Q; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Qin C; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Mao Y; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Lin Z; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Jiang H; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China., Zhu F; XellSmart Biopharmaceutical (Suzhou) Co., Ltd, Suzhou, China., Li X; XellSmart Biopharmaceutical (Suzhou) Co., Ltd, Suzhou, China., Geng X; Institute of Safety Evaluation, National Institutes for Food and Drug Control, Beijing, China.; Beijing Key Laboratory of Quality Control and Nonclinical Research and Evaluation for Cellular and Gene Therapy Medicinal Products, Beijing, China.
Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2026 Jan 02; Vol. 13, pp. 1701748. Date of Electronic Publication: 2026 Jan 02 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-634X
DOI:10.3389/fcell.2025.1701748