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Zn2+-mediated siRNA-doxorubicin self-assembled nanoparticles amplify Immunogenic cell death via aggravating redox dyshomeostasis for cancer therapy.

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Title: Zn2+-mediated siRNA-doxorubicin self-assembled nanoparticles amplify Immunogenic cell death via aggravating redox dyshomeostasis for cancer therapy.
Authors: Xiu J; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Liu L; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Yin L; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Peng Y; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Li Z; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Lin Z; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Song Y; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China., Yang D; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China. yangdg@stu.edu.cn.; Department of Pharmacy, Department of Dermatology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China. yangdg@stu.edu.cn., Zhang J; College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110000, PR China. zjl1160@163.com., Yang C; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China. yangchunrong@stu.edu.cn.; Department of Pharmacy, The Second Affiliated Hospital of Shantou, University Medical College, Shantou, 515041, China. yangchunrong@stu.edu.cn.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Jan 19; Vol. 24 (1), pp. 95. Date of Electronic Publication: 2026 Jan 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Zn<superscript>2+</superscript>-mediated siRNA-doxorubicin self-assembled nanoparticles amplify Immunogenic cell death via aggravating redox dyshomeostasis for cancer therapy.
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  Data: <searchLink fieldCode="AU" term="%22Xiu+J%22">Xiu J</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Yin+L%22">Yin L</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Peng+Y%22">Peng Y</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Song+Y%22">Song Y</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China.<br /><searchLink fieldCode="AU" term="%22Yang+D%22">Yang D</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China. yangdg@stu.edu.cn.; Department of Pharmacy, Department of Dermatology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China. yangdg@stu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110000, PR China. zjl1160@163.com.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Department of Pharmacy, Shantou University Medical College, No. 22 Xinling Road, Shantou, 515041, China. yangchunrong@stu.edu.cn.; Department of Pharmacy, The Second Affiliated Hospital of Shantou, University Medical College, Shantou, 515041, China. yangchunrong@stu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2026 Jan 19; Vol. 24 (1), pp. 95. <i>Date of Electronic Publication: </i>2026 Jan 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41555370
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        Value: 10.1186/s12951-025-04003-8
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        Text: English
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      – TitleFull: Zn2+-mediated siRNA-doxorubicin self-assembled nanoparticles amplify Immunogenic cell death via aggravating redox dyshomeostasis for cancer therapy.
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              Text: 2026 Jan 19
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              Y: 2026
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