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Crizotinib in Patients with Tumors with MET Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2.

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Title: Crizotinib in Patients with Tumors with MET Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2.
Authors: Coleman N; The University of Texas MD Anderson Cancer Center , Houston, Texas.; Trinity St. James's Cancer Institute, St. James's Hospital, Dublin, Ireland.; Trinity College Dublin, Dublin, Ireland., Wei Z; Trinity College Dublin, Dublin, Ireland., Iafrate AJ; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Zwiebel JA; Investigational Drug Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Sharon E; Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Gray RJ; Trinity College Dublin, Dublin, Ireland., Wang V; Trinity College Dublin, Dublin, Ireland., McShane LM; Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Rubinstein LV; Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Patton DR; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, Maryland., Williams PM; Frederick National Laboratory for Cancer Research , Frederick, Maryland., Hamilton SR; City of Hope National Medical Center and Comprehensive Cancer Center, Duarte, California., Takebe N; Developmental Therapeutics Clinic, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.; University of Oklahoma College of Medicine, Oklahoma City, Oklahoma., Williams T; Saint Luke's Cancer Institute, Boise, Idaho., Croley JJ; Saint Joseph Hospital , Lexington, Kentucky., Onitilo AA; Marshfield Medical Center, Weston, Wisconsin., Tricoli JV; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Cheng J; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Karlovich C; Frederick National Laboratory for Cancer Research , Frederick, Maryland., Conley BA; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Arteaga CL; UT Southwestern Simmons Comprehensive Cancer Center, Dallas, Texas., Harris L; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., O'Dwyer PJ; University of Pennsylvania , Philadelphia, Pennsylvania., Hong DS; The University of Texas MD Anderson Cancer Center , Houston, Texas., Chen AP; Developmental Therapeutics Clinic, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland., Flaherty KT; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Apr 01; Vol. 32 (7), pp. 1224-1233.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Crizotinib in Patients with Tumors with MET Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2.
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  Data: <searchLink fieldCode="AU" term="%22Coleman+N%22">Coleman N</searchLink>; The University of Texas MD Anderson Cancer Center , Houston, Texas.; Trinity St. James's Cancer Institute, St. James's Hospital, Dublin, Ireland.; Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Wei+Z%22">Wei Z</searchLink>; Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Iafrate+AJ%22">Iafrate AJ</searchLink>; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zwiebel+JA%22">Zwiebel JA</searchLink>; Investigational Drug Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Sharon+E%22">Sharon E</searchLink>; Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Gray+RJ%22">Gray RJ</searchLink>; Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Wang+V%22">Wang V</searchLink>; Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22McShane+LM%22">McShane LM</searchLink>; Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Rubinstein+LV%22">Rubinstein LV</searchLink>; Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Patton+DR%22">Patton DR</searchLink>; Center for Biomedical Informatics and Information Technology, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Williams+PM%22">Williams PM</searchLink>; Frederick National Laboratory for Cancer Research , Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Hamilton+SR%22">Hamilton SR</searchLink>; City of Hope National Medical Center and Comprehensive Cancer Center, Duarte, California.<br /><searchLink fieldCode="AU" term="%22Takebe+N%22">Takebe N</searchLink>; Developmental Therapeutics Clinic, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.; University of Oklahoma College of Medicine, Oklahoma City, Oklahoma.<br /><searchLink fieldCode="AU" term="%22Williams+T%22">Williams T</searchLink>; Saint Luke's Cancer Institute, Boise, Idaho.<br /><searchLink fieldCode="AU" term="%22Croley+JJ%22">Croley JJ</searchLink>; Saint Joseph Hospital , Lexington, Kentucky.<br /><searchLink fieldCode="AU" term="%22Onitilo+AA%22">Onitilo AA</searchLink>; Marshfield Medical Center, Weston, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Tricoli+JV%22">Tricoli JV</searchLink>; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Cheng+J%22">Cheng J</searchLink>; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Karlovich+C%22">Karlovich C</searchLink>; Frederick National Laboratory for Cancer Research , Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Conley+BA%22">Conley BA</searchLink>; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Arteaga+CL%22">Arteaga CL</searchLink>; UT Southwestern Simmons Comprehensive Cancer Center, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Harris+L%22">Harris L</searchLink>; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22O'Dwyer+PJ%22">O'Dwyer PJ</searchLink>; University of Pennsylvania , Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hong+DS%22">Hong DS</searchLink>; The University of Texas MD Anderson Cancer Center , Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chen+AP%22">Chen AP</searchLink>; Developmental Therapeutics Clinic, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Flaherty+KT%22">Flaherty KT</searchLink>; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2026 Apr 01; Vol. 32 (7), pp. 1224-1233.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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