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Multiple sources of β2*-nicotinic acetylcholine receptor binding are differentially affected during tobacco smoking abstinence as revealed by Independent Component Analysis of [18F]Flubatine PET images.

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Title: Multiple sources of β2*-nicotinic acetylcholine receptor binding are differentially affected during tobacco smoking abstinence as revealed by Independent Component Analysis of [18F]Flubatine PET images.
Authors: Raval NR; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. nakul.raval@yale.edu.; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. nakul.raval@yale.edu.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. nakul.raval@yale.edu., Calakos KC; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA., Zheng MQ; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA., Huttner A; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Esterlis I; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Huang H; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA., Calhoun VD; Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, GA, USA., Picciotto MR; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Cosgrove KP; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Hillmer AT; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. hillmera@med.umich.edu.; Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. hillmera@med.umich.edu.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. hillmera@med.umich.edu.; Department of Radiology, University of Michigan, Ann Arbor, MI, USA. hillmera@med.umich.edu.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 Jun; Vol. 51 (7), pp. 1207-1216. Date of Electronic Publication: 2026 Jan 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
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  Data: Multiple sources of β2*-nicotinic acetylcholine receptor binding are differentially affected during tobacco smoking abstinence as revealed by Independent Component Analysis of [<superscript>18</superscript>F]Flubatine PET images.
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