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Dietary silymarin improves gut-liver health by enhancing intestinal barrier integrity and modulating TLR4/NF-κB and NLRP3-mediated inflammatory responses in Aeromonas hydrophila-infected grass carp.

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Title: Dietary silymarin improves gut-liver health by enhancing intestinal barrier integrity and modulating TLR4/NF-κB and NLRP3-mediated inflammatory responses in Aeromonas hydrophila-infected grass carp.
Authors: Jia F; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China., Wei L; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China., Jiang WD; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China., Wu P; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China., Liu Y; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China., Ma YB; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China., Zhang HY; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China., Jin XW; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China., Ren HM; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China., Zhou XQ; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China. Electronic address: zhouxq@sicau.edu.cn., Feng L; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China. Electronic address: fenglin@sicau.edu.cn.
Source: Fish & shellfish immunology [Fish Shellfish Immunol] 2026 Mar; Vol. 170, pp. 111135. Date of Electronic Publication: 2026 Jan 19.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dietary silymarin improves gut-liver health by enhancing intestinal barrier integrity and modulating TLR4/NF-κB and NLRP3-mediated inflammatory responses in Aeromonas hydrophila-infected grass carp.
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  Data: <searchLink fieldCode="AU" term="%22Jia+F%22">Jia F</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China.<br /><searchLink fieldCode="AU" term="%22Wei+L%22">Wei L</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China.<br /><searchLink fieldCode="AU" term="%22Jiang+WD%22">Jiang WD</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China.<br /><searchLink fieldCode="AU" term="%22Wu+P%22">Wu P</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China.<br /><searchLink fieldCode="AU" term="%22Ma+YB%22">Ma YB</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China.<br /><searchLink fieldCode="AU" term="%22Zhang+HY%22">Zhang HY</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China.<br /><searchLink fieldCode="AU" term="%22Jin+XW%22">Jin XW</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China.<br /><searchLink fieldCode="AU" term="%22Ren+HM%22">Ren HM</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China.<br /><searchLink fieldCode="AU" term="%22Zhou+XQ%22">Zhou XQ</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China. Electronic address: zhouxq@sicau.edu.cn.<br /><searchLink fieldCode="AU" term="%22Feng+L%22">Feng L</searchLink>; Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Chengdu, 611130, China; Aquatic Health and Intelligent Aquaculture Key Laboratory of Sichuan Province, Chengdu, 610093, China. Electronic address: fenglin@sicau.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229505220%22">Fish & shellfish immunology</searchLink> [Fish Shellfish Immunol] 2026 Mar; Vol. 170, pp. 111135. <i>Date of Electronic Publication: </i>2026 Jan 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9505220 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9947 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210504648%22">10504648 </searchLink><i>NLM ISO Abbreviation: </i>Fish Shellfish Immunol <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.fsi.2026.111135
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      – Code: eng
        Text: English
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        StartPage: 111135
    Titles:
      – TitleFull: Dietary silymarin improves gut-liver health by enhancing intestinal barrier integrity and modulating TLR4/NF-κB and NLRP3-mediated inflammatory responses in Aeromonas hydrophila-infected grass carp.
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            – D: 01
              M: 03
              Text: 2026 Mar
              Type: published
              Y: 2026
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