First-in-human study to investigate the safety and efficacy of effective-mononuclear cell therapy for radiogenic xerostomia.
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| Title: | First-in-human study to investigate the safety and efficacy of effective-mononuclear cell therapy for radiogenic xerostomia. |
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| Authors: | I T; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Iwatake M; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Research Institute for Quantum and Chemical Innovation, Institutes of Innovation for Future Society, Nagoya University, Nagoya, Japan., Yoshida T; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Nagai K; Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan., Hotokezaka Y; Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Nishihara M; CellAxia Inc., Tokyo, Japan., Honma R; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Harada H; Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan., Hayashida M; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Nagano T; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kanai R; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Ohba S; Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Oral and Maxillofacial Surgery, Showa Medical University School of Dentistry, Tokyo, Japan., Yoshimura A; Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Masuda H; Shonan Research Institute of Innovative Medicine, Shonan Kamakura General Hospital, Kanagawa, Japan., Asahara T; Shonan Research Institute of Innovative Medicine, Shonan Kamakura General Hospital, Kanagawa, Japan., Miyazaki Y; Transfusion and Cell Therapy Unit, Nagasaki University Hospital, Nagasaki, Japan.; Department of Hematology, Atomic Bomb Disease Research Institute, Nagasaki University, Nagasaki, Japan., Kawakami A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Asahina I; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of oral surgery, Faculty of Medicine, Juntendo university, Tokyo, Japan., Seki M; CellAxia Inc., Tokyo, Japan., Sumita Y; Department of Medical Research and Development for Oral Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Regenerative Oral Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. |
| Source: | Regenerative therapy [Regen Ther] 2026 Jan 10; Vol. 31, pp. 101059. Date of Electronic Publication: 2026 Jan 10 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: The Japanese Society for Regenerative Medicine. Production and Hosting by Elsevier B.V Country of Publication: Netherlands NLM ID: 101709085 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-3204 (Electronic) Linking ISSN: 23523204 NLM ISO Abbreviation: Regen Ther Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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