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Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis.

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Title: Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis.
Authors: Nakano M; Department of Advanced Cardiorhythm Therapeutics, Chiba University Graduate School of Medicine, Chiba, Japan., Kondo Y; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan. Electronic address: yuusukondou-circ@umin.ac.jp., Fujiki S; Department of Cardiovascular Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Shiko Y; Department of Biostatistics, Graduate School of Medicine, Saitama Medical University, Saitama, Japan., Kawasaki Y; Department of Biostatistics, Graduate School of Medicine, Saitama Medical University, Saitama, Japan., Nakagawa Y; Department of Cardiovascular Medicine, Shiga University of Medical Science, Shiga, Japan., Takahashi K; Department of Cardiology, Niigata City General Hospital, Niigata, Japan., Okabe M; Department of Cardiology, Tachikawa General Hospital, Niigata, Japan., Kusano K; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan., Owada S; Department of Cardiology, Iwate Medical University Hospital, Iwate, Japan., Tsujita K; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Kubota Y; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan., Tomita H; Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine, Aomori, Japan., Anzai T; Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan., Iijima K; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan., Tanaka T; Clinical and Translational Research Center, Niigata University Medical and Dental Hospital, Niigata, Japan., Kobayashi Y; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan., Minamino T; Department of Cardiovascular Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Source: JACC. Asia [JACC Asia] 2026 May; Vol. 6 (5), pp. 748-758. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 9918452380106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-3747 (Electronic) Linking ISSN: 27723747 NLM ISO Abbreviation: JACC Asia Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis.
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  Data: <searchLink fieldCode="AU" term="%22Nakano+M%22">Nakano M</searchLink>; Department of Advanced Cardiorhythm Therapeutics, Chiba University Graduate School of Medicine, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Kondo+Y%22">Kondo Y</searchLink>; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan. Electronic address: yuusukondou-circ@umin.ac.jp.<br /><searchLink fieldCode="AU" term="%22Fujiki+S%22">Fujiki S</searchLink>; Department of Cardiovascular Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Shiko+Y%22">Shiko Y</searchLink>; Department of Biostatistics, Graduate School of Medicine, Saitama Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Kawasaki+Y%22">Kawasaki Y</searchLink>; Department of Biostatistics, Graduate School of Medicine, Saitama Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagawa+Y%22">Nakagawa Y</searchLink>; Department of Cardiovascular Medicine, Shiga University of Medical Science, Shiga, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Department of Cardiology, Niigata City General Hospital, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Okabe+M%22">Okabe M</searchLink>; Department of Cardiology, Tachikawa General Hospital, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Kusano+K%22">Kusano K</searchLink>; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Owada+S%22">Owada S</searchLink>; Department of Cardiology, Iwate Medical University Hospital, Iwate, Japan.<br /><searchLink fieldCode="AU" term="%22Tsujita+K%22">Tsujita K</searchLink>; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kubota+Y%22">Kubota Y</searchLink>; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tomita+H%22">Tomita H</searchLink>; Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine, Aomori, Japan.<br /><searchLink fieldCode="AU" term="%22Anzai+T%22">Anzai T</searchLink>; Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Iijima+K%22">Iijima K</searchLink>; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Clinical and Translational Research Center, Niigata University Medical and Dental Hospital, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+Y%22">Kobayashi Y</searchLink>; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Minamino+T%22">Minamino T</searchLink>; Department of Cardiovascular Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%229918452380106676%22">JACC. Asia</searchLink> [JACC Asia] 2026 May; Vol. 6 (5), pp. 748-758. <i>Date of Electronic Publication: </i>2026 Jan 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+on+behalf+of+the+American+College+of+Cardiology+Foundation%22">Elsevier on behalf of the American College of Cardiology Foundation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918452380106676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2772-3747 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227723747%22">27723747 </searchLink><i>NLM ISO Abbreviation: </i>JACC Asia <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.jacasi.2025.11.017
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        Text: English
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      – TitleFull: Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis.
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              Text: 2026 May
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