Optimizing expanded carrier screening for China: Multi-center study establishes 202-gene panel with optimal cost-effectiveness in preconception and prenatal care.
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| Title: | Optimizing expanded carrier screening for China: Multi-center study establishes 202-gene panel with optimal cost-effectiveness in preconception and prenatal care. |
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| Authors: | Yang Y; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China.; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China., Hang Y; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China.; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China., Cheng W; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China.; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China., Cao Y; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China.; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China., Wei Z; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China.; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China., Yuan J; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. |
| Source: | PloS one [PLoS One] 2026 Jan 22; Vol. 21 (1), pp. e0338642. Date of Electronic Publication: 2026 Jan 22 (Print Publication: 2026). |
| Publication Type: | Journal Article; Multicenter Study |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0338642 |
