Genomic evolution of pancreatic cancer at single-cell resolution.

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Title: Genomic evolution of pancreatic cancer at single-cell resolution.
Authors: Zhang H; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Valar Labs, Palo Alto, CA, USA., Sashittal P; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Department of Computer Science, Virginia Tech, Blacksburg, VA, USA., Karnoub ER; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA., Jakatdar A; Department of Computer Science, Princeton University, Princeton, NJ, USA., Umeda S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Hong J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Noronha AM; Marie-Josée & Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Cardenas A 3rd; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Erakky A; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., McIntyre CA; Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA., Hayashi A; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Pathology, Kyorin University, Mitaka-shi, Tokyo, Japan., Lecomte N; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Hilmi M; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Institut Curie, Paris, France., Park W; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York City, NY, USA., Pang N; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., O'Reilly EM; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York City, NY, USA., Wei AC; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York City, NY, USA.; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Raphael BJ; Department of Computer Science, Princeton University, Princeton, NJ, USA. braphael@princeton.edu., Iacobuzio-Donahue CA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. iacobuzc@mskcc.org.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. iacobuzc@mskcc.org.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. iacobuzc@mskcc.org.
Source: Nature genetics [Nat Genet] 2026 Feb; Vol. 58 (2), pp. 355-365. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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  Data: Genomic evolution of pancreatic cancer at single-cell resolution.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Valar Labs, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sashittal+P%22">Sashittal P</searchLink>; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Department of Computer Science, Virginia Tech, Blacksburg, VA, USA.<br /><searchLink fieldCode="AU" term="%22Karnoub+ER%22">Karnoub ER</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Jakatdar+A%22">Jakatdar A</searchLink>; Department of Computer Science, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Umeda+S%22">Umeda S</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hong+J%22">Hong J</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Noronha+AM%22">Noronha AM</searchLink>; Marie-Josée & Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cardenas+A+3rd%22">Cardenas A 3rd</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Erakky+A%22">Erakky A</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22McIntyre+CA%22">McIntyre CA</searchLink>; Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hayashi+A%22">Hayashi A</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Pathology, Kyorin University, Mitaka-shi, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Lecomte+N%22">Lecomte N</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hilmi+M%22">Hilmi M</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Institut Curie, Paris, France.<br /><searchLink fieldCode="AU" term="%22Park+W%22">Park W</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pang+N%22">Pang N</searchLink>; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22O'Reilly+EM%22">O'Reilly EM</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wei+AC%22">Wei AC</searchLink>; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Department of Medicine, Weill Cornell Medicine, New York City, NY, USA.; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Raphael+BJ%22">Raphael BJ</searchLink>; Department of Computer Science, Princeton University, Princeton, NJ, USA. braphael@princeton.edu.<br /><searchLink fieldCode="AU" term="%22Iacobuzio-Donahue+CA%22">Iacobuzio-Donahue CA</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. iacobuzc@mskcc.org.; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. iacobuzc@mskcc.org.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. iacobuzc@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2026 Feb; Vol. 58 (2), pp. 355-365. <i>Date of Electronic Publication: </i>2026 Jan 22.
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