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Acetylsalicylic acid disrupts SARS-CoV-2 spike protein glycosylation and selectively impairs binding to ACE2.

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Title: Acetylsalicylic acid disrupts SARS-CoV-2 spike protein glycosylation and selectively impairs binding to ACE2.
Authors: Perico L; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Bovio A; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Tomasoni S; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Trionfini P; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Cerullo D; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Corna D; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Pezzotta A; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Locatelli M; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Alberti M; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Benigni A; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Remuzzi G; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 07; Vol. 16, pp. 1706997. Date of Electronic Publication: 2026 Jan 07 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Acetylsalicylic acid disrupts SARS-CoV-2 spike protein glycosylation and selectively impairs binding to ACE2.
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  Data: <searchLink fieldCode="AU" term="%22Perico+L%22">Perico L</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Bovio+A%22">Bovio A</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Tomasoni+S%22">Tomasoni S</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Trionfini+P%22">Trionfini P</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Cerullo+D%22">Cerullo D</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Corna+D%22">Corna D</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Pezzotta+A%22">Pezzotta A</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Locatelli+M%22">Locatelli M</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Alberti+M%22">Alberti M</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Benigni+A%22">Benigni A</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Remuzzi+G%22">Remuzzi G</searchLink>; Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jan 07; Vol. 16, pp. 1706997. <i>Date of Electronic Publication: </i>2026 Jan 07 (<i>Print Publication: </i>2025).
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