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Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.

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Title: Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.
Authors: Wearn A, Onuska KM, Shanks HRC, Gaurav R, Lehéricy S, Baracchini G, Hughes C, Tremblay-Mercier J, Narayanan S, Breitner J, Poirier J, Schmitz TW, Turner GR, Spreng RN
Corporate Authors: PREVENT-AD Research Group
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 05. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41573824
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Wearn+A%22">Wearn A</searchLink><br /><searchLink fieldCode="AU" term="%22Onuska+KM%22">Onuska KM</searchLink><br /><searchLink fieldCode="AU" term="%22Shanks+HRC%22">Shanks HRC</searchLink><br /><searchLink fieldCode="AU" term="%22Gaurav+R%22">Gaurav R</searchLink><br /><searchLink fieldCode="AU" term="%22Lehéricy+S%22">Lehéricy S</searchLink><br /><searchLink fieldCode="AU" term="%22Baracchini+G%22">Baracchini G</searchLink><br /><searchLink fieldCode="AU" term="%22Hughes+C%22">Hughes C</searchLink><br /><searchLink fieldCode="AU" term="%22Tremblay-Mercier+J%22">Tremblay-Mercier J</searchLink><br /><searchLink fieldCode="AU" term="%22Narayanan+S%22">Narayanan S</searchLink><br /><searchLink fieldCode="AU" term="%22Breitner+J%22">Breitner J</searchLink><br /><searchLink fieldCode="AU" term="%22Poirier+J%22">Poirier J</searchLink><br /><searchLink fieldCode="AU" term="%22Schmitz+TW%22">Schmitz TW</searchLink><br /><searchLink fieldCode="AU" term="%22Turner+GR%22">Turner GR</searchLink><br /><searchLink fieldCode="AU" term="%22Spreng+RN%22">Spreng RN</searchLink>
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  Data: <searchLink fieldCode="CA" term="%22PREVENT-AD+Research+Group%22">PREVENT-AD Research Group</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Dec 05. <i>Date of Electronic Publication: </i>2025 Dec 05.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41573824
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      – Type: doi
        Value: 10.64898/2025.12.02.691923
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      – Code: eng
        Text: English
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      – TitleFull: Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.
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            – D: 05
              M: 12
              Text: 2025 Dec 05
              Type: published
              Y: 2025
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