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High-resolution promoter interaction analysis implicates genes involved in the activation of Type 3 Innate Lymphoid Cells in autoimmune disease risk.

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Title: High-resolution promoter interaction analysis implicates genes involved in the activation of Type 3 Innate Lymphoid Cells in autoimmune disease risk.
Authors: Malysheva V; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK.; VIB, Center for Molecular Neurology, Antwerp, 2610, Belgium.; Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp 2000, Belgium.; VIB, Center for AI and Computational Biology, Leuven, 2610, Belgium.; Trinity Hall, University of Cambridge, Cambridge, UK., Ray-Jones H; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK.; VIB, Center for Molecular Neurology, Antwerp, 2610, Belgium.; Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Lakes N; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Brown RA; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH 43210, USA., Cazares TA; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Clay O; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Ohayon DE; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Artemov P; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK., Wayman JA; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Yang ZF; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Della Rosa M; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK., Petitjean C; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK., Booth C; Center for Genetics and Rare Diseases, Sanford Research, Sioux Falls, SD 57104, USA., Ellaway JIJ; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK., Barnes JR; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Dangel AW; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH 43210, USA., Saini A; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH 43210, USA., Orchard WR; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; University of Cambridge, Cambridge, UK., Chen X; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Parameswaran S; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Burden F; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK., Frontini M; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.; National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter Medical School, Exeter, UK., Nagano T; The Babraham Institute, Cambridge, CB22 3AT, UK., Fraser P; The Babraham Institute, Cambridge, CB22 3AT, UK.; Florida State University, Department of Biological Sciences, Florida State University, Tallahassee, FL 32306-4295, USA., Schoenfelder S; The Babraham Institute, Cambridge, CB22 3AT, UK., Weirauch MT; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Kottyan LC; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Smith DF; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Department of Otolaryngology, Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Divisions of Pediatric Otolaryngology and Pulmonary & Sleep Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Powell N; Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK., Weimer JM; Center for Genetics and Rare Diseases, Sanford Research, Sioux Falls, SD 57104, USA., Oltz EM; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH 43210, USA., Wallace C; MRC Biostatistics Unit, Cambridge Biomedical Campus, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 0SR, UK.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0AW., Miraldi ER; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Waggoner S; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Spivakov M; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 10. Date of Electronic Publication: 2026 Jan 10.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: High-resolution promoter interaction analysis implicates genes involved in the activation of Type 3 Innate Lymphoid Cells in autoimmune disease risk.
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  Data: <searchLink fieldCode="AU" term="%22Malysheva+V%22">Malysheva V</searchLink>; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK.; VIB, Center for Molecular Neurology, Antwerp, 2610, Belgium.; Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp 2000, Belgium.; VIB, Center for AI and Computational Biology, Leuven, 2610, Belgium.; Trinity Hall, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ray-Jones+H%22">Ray-Jones H</searchLink>; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK.; VIB, Center for Molecular Neurology, Antwerp, 2610, Belgium.; Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Lakes+N%22">Lakes N</searchLink>; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; 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Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Smith+DF%22">Smith DF</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Department of Otolaryngology, Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Divisions of Pediatric Otolaryngology and Pulmonary & Sleep Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Powell+N%22">Powell N</searchLink>; 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Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Waggoner+S%22">Waggoner S</searchLink>; Immunology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.; Division of Human Genetics and Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Spivakov+M%22">Spivakov M</searchLink>; MRC Laboratory of Medical Sciences, London W12 0HS, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0HS, UK.
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