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Strategic aptamer evolution for SARS-CoV-2 to enable the detection in human saliva.

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Title: Strategic aptamer evolution for SARS-CoV-2 to enable the detection in human saliva.
Authors: Miura D; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan; Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 3-8-1 Harumi-cho, Fuchu, Tokyo, 183-8538, Japan., Hayashi W; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan., Nashiki S; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan., Oguchi K; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan., Kawai H; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan., Tsukakoshi K; Department of Chemistry, Faculty of Science Division I, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku, Tokyo, 162-8601, Japan., Tsugawa W; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan., Asano R; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan. Electronic address: ryutaroa@cc.tuat.ac.jp., Ikebukuro K; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan. Electronic address: ikebu@cc.tuat.ac.jp.
Source: Biosensors & bioelectronics [Biosens Bioelectron] 2026 Apr 15; Vol. 298, pp. 118423. Date of Electronic Publication: 2026 Jan 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE
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  Data: Strategic aptamer evolution for SARS-CoV-2 to enable the detection in human saliva.
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  Data: <searchLink fieldCode="AU" term="%22Miura+D%22">Miura D</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan; Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 3-8-1 Harumi-cho, Fuchu, Tokyo, 183-8538, Japan.<br /><searchLink fieldCode="AU" term="%22Hayashi+W%22">Hayashi W</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.<br /><searchLink fieldCode="AU" term="%22Nashiki+S%22">Nashiki S</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.<br /><searchLink fieldCode="AU" term="%22Oguchi+K%22">Oguchi K</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.<br /><searchLink fieldCode="AU" term="%22Kawai+H%22">Kawai H</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.<br /><searchLink fieldCode="AU" term="%22Tsukakoshi+K%22">Tsukakoshi K</searchLink>; Department of Chemistry, Faculty of Science Division I, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku, Tokyo, 162-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Tsugawa+W%22">Tsugawa W</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+R%22">Asano R</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan. Electronic address: ryutaroa@cc.tuat.ac.jp.<br /><searchLink fieldCode="AU" term="%22Ikebukuro+K%22">Ikebukuro K</searchLink>; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan. Electronic address: ikebu@cc.tuat.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%229001289%22">Biosensors & bioelectronics</searchLink> [Biosens Bioelectron] 2026 Apr 15; Vol. 298, pp. 118423. <i>Date of Electronic Publication: </i>2026 Jan 19.
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        Value: 10.1016/j.bios.2026.118423
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              Text: 2026 Apr 15
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