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The efficacy and safety of high versus low doses of intravenous intraoperative tranexamic acid during spinal fusion in patients with adolescent idiopathic scoliosis: a network meta-analysis of randomized controlled trials.

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Title: The efficacy and safety of high versus low doses of intravenous intraoperative tranexamic acid during spinal fusion in patients with adolescent idiopathic scoliosis: a network meta-analysis of randomized controlled trials.
Authors: Anaspure OS; Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19140, USA., Baumann AN; Department of Orthopaedic Surgery, Cleveland Clinic Akron General, Akron, OH, USA., Talaski GM; Department of Mechanical Engineering, University of Iowa, Iowa City, IA, USA., Villers M; College of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA., Baldwin KD; Department of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Source: Spine deformity [Spine Deform] 2026 Jan 24. Date of Electronic Publication: 2026 Jan 24.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101603979 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-1358 (Electronic) Linking ISSN: 2212134X NLM ISO Abbreviation: Spine Deform Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Anaspure+OS%22">Anaspure OS</searchLink>; Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Baumann+AN%22">Baumann AN</searchLink>; Department of Orthopaedic Surgery, Cleveland Clinic Akron General, Akron, OH, USA.<br /><searchLink fieldCode="AU" term="%22Talaski+GM%22">Talaski GM</searchLink>; Department of Mechanical Engineering, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Villers+M%22">Villers M</searchLink>; College of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.<br /><searchLink fieldCode="AU" term="%22Baldwin+KD%22">Baldwin KD</searchLink>; Department of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101603979 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2212-1358 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222212134X%22">2212134X </searchLink><i>NLM ISO Abbreviation: </i>Spine Deform <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s43390-026-01289-y
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        Text: English
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      – TitleFull: The efficacy and safety of high versus low doses of intravenous intraoperative tranexamic acid during spinal fusion in patients with adolescent idiopathic scoliosis: a network meta-analysis of randomized controlled trials.
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              Text: 2026 Jan 24
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