Epigenetic alterations of AKT1 orchestrate a metabolic reprogramming in advanced lipedema: translational insights from an integrated multi-omics study.
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| Title: | Epigenetic alterations of AKT1 orchestrate a metabolic reprogramming in advanced lipedema: translational insights from an integrated multi-omics study. |
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| Authors: | Santella B; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Salerno, 84081, Italy.; National Biodiversity Future Center (NBFC), Palermo, 90133, Italy., Salvati A; Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Salerno, Italy.; Postgraduate School in Clinical Pathology and Clinical Biochemistry, University of Salerno, Baronissi, Salerno, Italy., Papp A; P-Health Medical Solution, F.-W.-Raiffeisenstraße 1b, Elsbethen, Salzburg, 5061, Austria., D'Ursi A; National Biodiversity Future Center (NBFC), Palermo, 90133, Italy.; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno, 84084, Italy., Memoli D; Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Salerno, Italy., Mingo M; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Salerno, 84081, Italy., Pulai C; P-Health Medical Solution, F.-W.-Raiffeisenstraße 1b, Elsbethen, Salzburg, 5061, Austria., Marino C; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno, 84084, Italy., Rastrelli L; National Biodiversity Future Center (NBFC), Palermo, 90133, Italy.; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno, 84084, Italy., D'Elia M; National Biodiversity Future Center (NBFC), Palermo, 90133, Italy.; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno, 84084, Italy., Nassa G; Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Salerno, Italy. gnassa@unisa.it.; Genome Research Center for Health - CRGS, Baronissi, Salerno, Italy. gnassa@unisa.it.; Molecular Pathology and Medical Genomics Unit, AOU 'S. Giovanni di Dio e Ruggi d'Aragona', University of Salerno, Salerno, Italy. gnassa@unisa.it., Schiavo L; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Salerno, 84081, Italy. lschiavo@unisa.it.; National Biodiversity Future Center (NBFC), Palermo, 90133, Italy. lschiavo@unisa.it. |
| Source: | Journal of translational medicine [J Transl Med] 2026 Jan 24; Vol. 24 (1), pp. 265. Date of Electronic Publication: 2026 Jan 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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