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Subgroup Modelling and Use of External Evidence in Precision Oncology Appraisals: An External Assessment Group Perspective on the NICE Single Technology Appraisal of Zolbetuximab for Untreated CLDN18.2-Positive HER2-Negative Unresectable Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma.

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Title: Subgroup Modelling and Use of External Evidence in Precision Oncology Appraisals: An External Assessment Group Perspective on the NICE Single Technology Appraisal of Zolbetuximab for Untreated CLDN18.2-Positive HER2-Negative Unresectable Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma.
Authors: Scholte M; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands. Mirre.Scholte@radboudumc.nl.; Departments of Radiology and IQ Health, Radboud University Medical Centre, Nijmegen, The Netherlands. Mirre.Scholte@radboudumc.nl., Fernández Coves A; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands., Yang H; Kleijnen Systematic Reviews Limited, York, UK., Armstrong N; Kleijnen Systematic Reviews Limited, York, UK., McDermott K; Kleijnen Systematic Reviews Limited, York, UK., Tian X; Kleijnen Systematic Reviews Limited, York, UK., Stirk L; Kleijnen Systematic Reviews Limited, York, UK., Wolff R; Kleijnen Systematic Reviews Limited, York, UK., Joore MA; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands., Grimm SE; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
Source: PharmacoEconomics [Pharmacoeconomics] 2026 May; Vol. 44 (5), pp. 509-513. Date of Electronic Publication: 2026 Jan 25.
Publication Type: Journal Article
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9212404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2027 (Electronic) Linking ISSN: 11707690 NLM ISO Abbreviation: Pharmacoeconomics Subsets: MEDLINE; In Process
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  Data: Subgroup Modelling and Use of External Evidence in Precision Oncology Appraisals: An External Assessment Group Perspective on the NICE Single Technology Appraisal of Zolbetuximab for Untreated CLDN18.2-Positive HER2-Negative Unresectable Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Scholte+M%22">Scholte M</searchLink>; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands. Mirre.Scholte@radboudumc.nl.; Departments of Radiology and IQ Health, Radboud University Medical Centre, Nijmegen, The Netherlands. Mirre.Scholte@radboudumc.nl.<br /><searchLink fieldCode="AU" term="%22Fernández+Coves+A%22">Fernández Coves A</searchLink>; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Kleijnen Systematic Reviews Limited, York, UK.<br /><searchLink fieldCode="AU" term="%22Armstrong+N%22">Armstrong N</searchLink>; Kleijnen Systematic Reviews Limited, York, UK.<br /><searchLink fieldCode="AU" term="%22McDermott+K%22">McDermott K</searchLink>; Kleijnen Systematic Reviews Limited, York, UK.<br /><searchLink fieldCode="AU" term="%22Tian+X%22">Tian X</searchLink>; Kleijnen Systematic Reviews Limited, York, UK.<br /><searchLink fieldCode="AU" term="%22Stirk+L%22">Stirk L</searchLink>; Kleijnen Systematic Reviews Limited, York, UK.<br /><searchLink fieldCode="AU" term="%22Wolff+R%22">Wolff R</searchLink>; Kleijnen Systematic Reviews Limited, York, UK.<br /><searchLink fieldCode="AU" term="%22Joore+MA%22">Joore MA</searchLink>; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Grimm+SE%22">Grimm SE</searchLink>; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9212404 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-2027 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211707690%22">11707690 </searchLink><i>NLM ISO Abbreviation: </i>Pharmacoeconomics <i>Subsets: </i>MEDLINE; In Process
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              Text: 2026 May
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