A Phase I, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravenous UMC119-06 in Patients with Acute Ischemic Stroke.

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Title: A Phase I, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravenous UMC119-06 in Patients with Acute Ischemic Stroke.
Authors: Chan L; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan., Chen JH; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan., Hong CT; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan., Lin YC; Meribank Biotech Co., Ltd., Taipei 114, Taiwan., Chang JH; Meribank Biotech Co., Ltd., Taipei 114, Taiwan., Chen CC; Meribank Biotech Co., Ltd., Taipei 114, Taiwan., Hsuan YC; Meribank Biotech Co., Ltd., Taipei 114, Taiwan.; Reon Biotech Co., Ltd., Taipei 114, Taiwan., Hu CJ; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan.
Source: International journal of medical sciences [Int J Med Sci] 2026 Jan 01; Vol. 23 (2), pp. 576-584. Date of Electronic Publication: 2026 Jan 01 (Print Publication: 2026).
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101213954 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-1907 (Electronic) Linking ISSN: 14491907 NLM ISO Abbreviation: Int J Med Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chan+L%22">Chan L</searchLink>; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+JH%22">Chen JH</searchLink>; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hong+CT%22">Hong CT</searchLink>; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YC%22">Lin YC</searchLink>; Meribank Biotech Co., Ltd., Taipei 114, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+JH%22">Chang JH</searchLink>; Meribank Biotech Co., Ltd., Taipei 114, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CC%22">Chen CC</searchLink>; Meribank Biotech Co., Ltd., Taipei 114, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsuan+YC%22">Hsuan YC</searchLink>; Meribank Biotech Co., Ltd., Taipei 114, Taiwan.; Reon Biotech Co., Ltd., Taipei 114, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hu+CJ%22">Hu CJ</searchLink>; Department of Neurology, school of medicine, college of medicine, Taipei Medical University, Taipei, Taiwan.; Department of Neurology, Taipei Medical University - Shuang Ho Hospital, New Taipei, Taiwan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101213954 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1449-1907 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214491907%22">14491907 </searchLink><i>NLM ISO Abbreviation: </i>Int J Med Sci <i>Subsets: </i>MEDLINE
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      – TitleFull: A Phase I, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravenous UMC119-06 in Patients with Acute Ischemic Stroke.
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              Text: 2026 Jan 01
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