Single-cell and transcriptomic profiling reveal stemness-driven immune evasion in obstructive sleep apnea (OSA) associated lung cancer.
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| Title: | Single-cell and transcriptomic profiling reveal stemness-driven immune evasion in obstructive sleep apnea (OSA) associated lung cancer. |
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| Authors: | Liu YW; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan., Wu CJ; Nursing Department, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; College of Nursing, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan., Chang KF; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Division of Experimental Surgery Center, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Lee YK; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Division of Experimental Surgery Center, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan., Lin HR; Nursing Department, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan., Ko CC; Department of Medical Imaging, Chi-Mei Medical Center, Tainan 710402, Taiwan.; Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan.; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan., Hsieh CB; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan., Chang CH; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Division of Experimental Surgery Center, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Lin CH; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan., Chen BS; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan., Solomon DD; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan., Kumar S; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, 173229, India., Palekkode N; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.; Department of Biotechnology, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, 624101, India., Fathima A; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.; Computer Engineering with specialization in Artificial Intelligence and Machine Learning, Presidency University, Yelahanka, Bengaluru 560064 India., Xuan DTM; Faculty of Pharmacy, Van Lang University, 69/68 Dang Thuy Tram Street, Ward 13, Binh Thanh District, Ho Chi Minh City 70000, Vietnam., Nguyen NUN; Center for Regenerative Medicine, University of South Florida Health Heart Institute, Tampa, Florida 33602, USA.; Division of Cardiology, Department of Internal Medicine, Morsani School of Medicine, University of South Florida, Tampa, Florida 33602, USA., Waikhom J; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan., Yuan CH; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.; Department of Otolaryngology, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Department of Otolaryngology, National Defense Medical University, Taipei 11490, Taiwan., Wu YJ; Department of Surgery, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan. |
| Source: | Journal of Cancer [J Cancer] 2026 Jan 01; Vol. 17 (2), pp. 316-337. Date of Electronic Publication: 2026 Jan 01 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101535920 Publication Model: eCollection Cited Medium: Print ISSN: 1837-9664 (Print) Linking ISSN: 18379664 NLM ISO Abbreviation: J Cancer Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41584048 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Single-cell and transcriptomic profiling reveal stemness-driven immune evasion in obstructive sleep apnea (OSA) associated lung cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Liu+YW%22">Liu YW</searchLink>; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+CJ%22">Wu CJ</searchLink>; Nursing Department, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; College of Nursing, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+KF%22">Chang KF</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Division of Experimental Surgery Center, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+YK%22">Lee YK</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Division of Experimental Surgery Center, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+HR%22">Lin HR</searchLink>; Nursing Department, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ko+CC%22">Ko CC</searchLink>; Department of Medical Imaging, Chi-Mei Medical Center, Tainan 710402, Taiwan.; Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan.; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+CB%22">Hsieh CB</searchLink>; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CH%22">Chang CH</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Division of Experimental Surgery Center, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CH%22">Lin CH</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+BS%22">Chen BS</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.<br /><searchLink fieldCode="AU" term="%22Solomon+DD%22">Solomon DD</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; Faculty of Applied Sciences and Biotechnology, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, 173229, India.<br /><searchLink fieldCode="AU" term="%22Palekkode+N%22">Palekkode N</searchLink>; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.; Department of Biotechnology, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, 624101, India.<br /><searchLink fieldCode="AU" term="%22Fathima+A%22">Fathima A</searchLink>; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.; Computer Engineering with specialization in Artificial Intelligence and Machine Learning, Presidency University, Yelahanka, Bengaluru 560064 India.<br /><searchLink fieldCode="AU" term="%22Xuan+DTM%22">Xuan DTM</searchLink>; Faculty of Pharmacy, Van Lang University, 69/68 Dang Thuy Tram Street, Ward 13, Binh Thanh District, Ho Chi Minh City 70000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Nguyen+NUN%22">Nguyen NUN</searchLink>; Center for Regenerative Medicine, University of South Florida Health Heart Institute, Tampa, Florida 33602, USA.; Division of Cardiology, Department of Internal Medicine, Morsani School of Medicine, University of South Florida, Tampa, Florida 33602, USA.<br /><searchLink fieldCode="AU" term="%22Waikhom+J%22">Waikhom J</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yuan+CH%22">Yuan CH</searchLink>; Medical Laboratory, Medical Education and Research Center, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.; Department of Otolaryngology, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan.; Department of Otolaryngology, National Defense Medical University, Taipei 11490, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+YJ%22">Wu YJ</searchLink>; Department of Surgery, Kaohsiung Armed Forces General Hospital, National Defense Medical University, Kaohsiung 80284, Taiwan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101535920%22">Journal of Cancer</searchLink> [J Cancer] 2026 Jan 01; Vol. 17 (2), pp. 316-337. <i>Date of Electronic Publication: </i>2026 Jan 01 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101535920 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1837-9664 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218379664%22">18379664 </searchLink><i>NLM ISO Abbreviation: </i>J Cancer <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41584048 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7150/jca.126708 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 316 Titles: – TitleFull: Single-cell and transcriptomic profiling reveal stemness-driven immune evasion in obstructive sleep apnea (OSA) associated lung cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Liu YW – PersonEntity: Name: NameFull: Wu CJ – PersonEntity: Name: NameFull: Chang KF – PersonEntity: Name: NameFull: Lee YK – PersonEntity: Name: NameFull: Lin HR – PersonEntity: Name: NameFull: Ko CC – PersonEntity: Name: NameFull: Hsieh CB – PersonEntity: Name: NameFull: Chang CH – PersonEntity: Name: NameFull: Lin CH – PersonEntity: Name: NameFull: Chen BS – PersonEntity: Name: NameFull: Solomon DD – PersonEntity: Name: NameFull: Kumar S – PersonEntity: Name: NameFull: Palekkode N – PersonEntity: Name: NameFull: Fathima A – PersonEntity: Name: NameFull: Xuan DTM – PersonEntity: Name: NameFull: Nguyen NUN – PersonEntity: Name: NameFull: Waikhom J – PersonEntity: Name: NameFull: Yuan CH – PersonEntity: Name: NameFull: Wu YJ IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2026 Jan 01 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1837-9664 Numbering: – Type: volume Value: 17 – Type: issue Value: 2 Titles: – TitleFull: Journal of Cancer Type: main |
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