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Purifying selection on deleterious variants affected by the combination of subgenomes and gene expression in bread wheat.

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Title: Purifying selection on deleterious variants affected by the combination of subgenomes and gene expression in bread wheat.
Authors: Halstead-Nussloch G; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland., Okada M; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Kihara Institute for Biological Research, Yokohama City University, Yokohama 244-0813, Japan; Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan., Haberer G; Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany., Lux T; Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany., Islam ASMF; Institute for Advancing Health Through Agriculture, Texas A&M, College Station, TX, USA., Hatakeyama M; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Functional Genomics Center Zurich, 8057 Zurich, Switzerland., Briskine R; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Science IT, University of Zurich, 8057 Zurich, Switzerland., White B; Earlham Institute, Norwich Research Park, Norwich NR4 7UH, UK., Hall A; Earlham Institute, Norwich Research Park, Norwich NR4 7UH, UK., Pozniak C; Crop Development Centre and Department of Plant Sciences, University of Saskatchewan, Saskatoon, SK, Canada., Spannagl M; Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany., Paape T; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; USDA-ARS Responsive Agriculture Food Systems Research Unit, College Station, TX, USA; Department of Soil and Crop Sciences, Texas A&M, College Station, TX, USA. Electronic address: timothy.paape@usda.gov., Shimizu KK; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Kihara Institute for Biological Research, Yokohama City University, Yokohama 244-0813, Japan. Electronic address: kentaro.shimizu@uzh.ch.
Corporate Authors: 10+ Wheat Genome Project
Source: Cell reports [Cell Rep] 2026 Feb 24; Vol. 45 (2), pp. 116785. Date of Electronic Publication: 2026 Jan 26.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Halstead-Nussloch+G%22">Halstead-Nussloch G</searchLink>; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Okada+M%22">Okada M</searchLink>; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Kihara Institute for Biological Research, Yokohama City University, Yokohama 244-0813, Japan; Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan.<br /><searchLink fieldCode="AU" term="%22Haberer+G%22">Haberer G</searchLink>; Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lux+T%22">Lux T</searchLink>; Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Islam+ASMF%22">Islam ASMF</searchLink>; Institute for Advancing Health Through Agriculture, Texas A&M, College Station, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hatakeyama+M%22">Hatakeyama M</searchLink>; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Functional Genomics Center Zurich, 8057 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Briskine+R%22">Briskine R</searchLink>; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Science IT, University of Zurich, 8057 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22White+B%22">White B</searchLink>; Earlham Institute, Norwich Research Park, Norwich NR4 7UH, UK.<br /><searchLink fieldCode="AU" term="%22Hall+A%22">Hall A</searchLink>; Earlham Institute, Norwich Research Park, Norwich NR4 7UH, UK.<br /><searchLink fieldCode="AU" term="%22Pozniak+C%22">Pozniak C</searchLink>; Crop Development Centre and Department of Plant Sciences, University of Saskatchewan, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Spannagl+M%22">Spannagl M</searchLink>; Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Paape+T%22">Paape T</searchLink>; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; USDA-ARS Responsive Agriculture Food Systems Research Unit, College Station, TX, USA; Department of Soil and Crop Sciences, Texas A&M, College Station, TX, USA. Electronic address: timothy.paape@usda.gov.<br /><searchLink fieldCode="AU" term="%22Shimizu+KK%22">Shimizu KK</searchLink>; Department of Evolutionary Biology and Environmental Studies, University of Zurich, 8057 Zurich, Switzerland; Kihara Institute for Biological Research, Yokohama City University, Yokohama 244-0813, Japan. Electronic address: kentaro.shimizu@uzh.ch.
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