Construction of anti-HER2 affibody-directed CAR-NK and its synergistic effects with doxorubicin-loaded nanodrug against HER2-positive breast cancer.

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Title: Construction of anti-HER2 affibody-directed CAR-NK and its synergistic effects with doxorubicin-loaded nanodrug against HER2-positive breast cancer.
Authors: He X; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China., Liang Z; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China., Liu Q; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China., Zhang X; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China., Liang H; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China., Jia R; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China., Sheng W; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 12; Vol. 16, pp. 1692107. Date of Electronic Publication: 2026 Jan 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Construction of anti-HER2 affibody-directed CAR-NK and its synergistic effects with doxorubicin-loaded nanodrug against HER2-positive breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22He+X%22">He X</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Liang+Z%22">Liang Z</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liang+H%22">Liang H</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jia+R%22">Jia R</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sheng+W%22">Sheng W</searchLink>; Beijing International Science and Technology, Cooperation Base of Antivirus Drug, College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jan 12; Vol. 16, pp. 1692107. <i>Date of Electronic Publication: </i>2026 Jan 12 (<i>Print Publication: </i>2025).
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        Value: 10.3389/fimmu.2025.1692107
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      – TitleFull: Construction of anti-HER2 affibody-directed CAR-NK and its synergistic effects with doxorubicin-loaded nanodrug against HER2-positive breast cancer.
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              Text: 2026 Jan 12
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