View in EDS

Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming.

Saved in:
Bibliographic Details
Title: Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming.
Authors: Wang Y; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Yinuo.Wang@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany. Yinuo.Wang@medma.uni-heidelberg.de., Shi H; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Wittig J; Department of Vascular Dysfunction, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany., Ren Y; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Cordero J; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany., Dewenter M; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Institute of Experimental Cardiology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany., Mella J; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Buchwalter A; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Backs J; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Institute of Experimental Cardiology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany., Wieland T; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Experimental Pharmacology, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Heineke J; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany.; Department of Cardiovascular Physiology, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Fleming I; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany., Bibli SI; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany. Iris.Bibli@medma.uni-heidelberg.de.; Department of Vascular Dysfunction, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Iris.Bibli@medma.uni-heidelberg.de.; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany. Iris.Bibli@medma.uni-heidelberg.de.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany. Iris.Bibli@medma.uni-heidelberg.de., Dobreva G; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.
Source: Nature metabolism [Nat Metab] 2026 Feb; Vol. 8 (2), pp. 431-453. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41606307
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Yinuo.Wang@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany. Yinuo.Wang@medma.uni-heidelberg.de.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Wittig+J%22">Wittig J</searchLink>; Department of Vascular Dysfunction, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Cordero+J%22">Cordero J</searchLink>; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Dewenter+M%22">Dewenter M</searchLink>; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Institute of Experimental Cardiology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mella+J%22">Mella J</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Buchwalter+A%22">Buchwalter A</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Backs+J%22">Backs J</searchLink>; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Institute of Experimental Cardiology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wieland+T%22">Wieland T</searchLink>; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Experimental Pharmacology, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Heineke+J%22">Heineke J</searchLink>; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany.; Department of Cardiovascular Physiology, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Fleming+I%22">Fleming I</searchLink>; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany.; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Bibli+SI%22">Bibli SI</searchLink>; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany. Iris.Bibli@medma.uni-heidelberg.de.; Department of Vascular Dysfunction, ECAS, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Iris.Bibli@medma.uni-heidelberg.de.; Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany. Iris.Bibli@medma.uni-heidelberg.de.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany. Iris.Bibli@medma.uni-heidelberg.de.<br /><searchLink fieldCode="AU" term="%22Dobreva+G%22">Dobreva G</searchLink>; Department of Cardiovascular Genomics and Epigenomics, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.; German Centre for Cardiovascular Research (DZHK), Heidelberg/Mannheim, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany. Gergana.Dobreva@medma.uni-heidelberg.de.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2026 Feb; Vol. 8 (2), pp. 431-453. <i>Date of Electronic Publication: </i>2026 Jan 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101736592 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2522-5812 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225225812%22">25225812 </searchLink><i>NLM ISO Abbreviation: </i>Nat Metab <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41606307
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s42255-025-01443-2
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 431
    Titles:
      – TitleFull: Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Shi H
      – PersonEntity:
          Name:
            NameFull: Wittig J
      – PersonEntity:
          Name:
            NameFull: Ren Y
      – PersonEntity:
          Name:
            NameFull: Cordero J
      – PersonEntity:
          Name:
            NameFull: Dewenter M
      – PersonEntity:
          Name:
            NameFull: Mella J
      – PersonEntity:
          Name:
            NameFull: Buchwalter A
      – PersonEntity:
          Name:
            NameFull: Backs J
      – PersonEntity:
          Name:
            NameFull: Wieland T
      – PersonEntity:
          Name:
            NameFull: Heineke J
      – PersonEntity:
          Name:
            NameFull: Fleming I
      – PersonEntity:
          Name:
            NameFull: Bibli SI
      – PersonEntity:
          Name:
            NameFull: Dobreva G
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2522-5812
          Numbering:
            – Type: volume
              Value: 8
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Nature metabolism
              Type: main
ResultId 1