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Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes.

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Title: Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes.
Authors: Aoki T; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada.; University of Toronto, Toronto, Canada., Duns G; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Rai S; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Japan., Jiang A; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Lytle A; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Yin Y; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Kishida M; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Yu Li M; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Lee C; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Smorra D; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Hilton LK; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Healy S; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Alig SK; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, California., Shahrokh Esfahani M; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, California., Sarkozy C; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Hematology Department, Institut Curie, Saint Cloud, France., Hung SS; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Milne K; Deeley Research Centre, BC Cancer, Victoria, Canada., Telenius A; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., O'Brien L; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Wong JCH; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Cassidy C; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Fujisawa M; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Strong C; Deeley Research Centre, BC Cancer, Victoria, Canada., Goodyear T; Deeley Research Centre, BC Cancer, Victoria, Canada.; University of Limerick School of Medicine, Limerick, Ireland., Di Vito C; Deeley Research Centre, BC Cancer, Victoria, Canada., Luksik C; Deeley Research Centre, BC Cancer, Victoria, Canada., Edin G; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Gonzalez L; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Rangel Patiño J; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada., Hong M; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada., Wu S; Department of Molecular Oncology, BC Cancer, Vancouver, Canada., Lee E; Department of Molecular Oncology, BC Cancer, Vancouver, Canada., Sakhdari A; Laboratory Medicine and Pathobiology Department, University Health Network, Toronto, Canada., Takata K; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Pathology, Faculty of Medicine, Academic Research Division, University of Toyama, Toyama, Japan., Miyata-Takata T; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Boyle M; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Ben-Neriah S; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Weng AP; Terry Fox Laboratory, BC Cancer, Vancouver, Canada., Xu A; Cedars-Sinai Medical Center , Los Angeles, California., Merchant A; Cedars-Sinai Medical Center , Los Angeles, California., Roth A; Department of Molecular Oncology, BC Cancer, Vancouver, Canada., Crump M; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada., Kuruvilla J; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada., Prica A; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada., Kridel R; Princess Margaret Cancer Centre , University Health Network, Toronto, Canada., Huntsman DG; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Nelson BH; Deeley Research Centre, BC Cancer, Victoria, Canada., Farinha P; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Morin RD; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada., Alizadeh AA; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, California., Savage KJ; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Medicine, University of British Columbia, Vancouver, Canada., Scott DW; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Medicine, University of British Columbia, Vancouver, Canada., Steidl C; Centre for Lymphoid Cancer, BC Cancer, Vancouver, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Source: Cancer discovery [Cancer Discov] 2026 May 01; Vol. 16 (5), pp. 993-1013.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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