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Circadian feeding promotion by Ninjin'yoeito counteracts frailty in aged mice.

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Title: Circadian feeding promotion by Ninjin'yoeito counteracts frailty in aged mice.
Authors: Wang L; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Kobe Biotechnology Research and Human Resource Development Center, Kobe University Graduate School of Medicine, Kobe 650-0047, Japan; Division of Health Sciences, Medicine and Aging, Bin Zhou Polytechnic, Binzhou 256-603, China., Rakhat Y; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan., Nakata M; Department of Physiology, Faculty of Medicine, Wakayama Medical University School of Medicine, Wakayama 641-8509, Japan., Dezaki K; Faculty of Pharmacy, Iryo Sosei University, Iwaki, Japan., Kuwata H; Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan., Zhang B; Department of Physiology, Faculty of Medicine, Wakayama Medical University School of Medicine, Wakayama 641-8509, Japan., Han W; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Kobe Biotechnology Research and Human Resource Development Center, Kobe University Graduate School of Medicine, Kobe 650-0047, Japan., Banno S; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan., Abe C; Department of Physiology, University of Fukui School of Medical Sciences, Fukui 910-1193, Japan., Ogiso N; Faculty of Health and Medical Sciences, Aichi Syukutoku University, Nagakute, 480-1197, Japan., Sakurai T; Department of Prevention and Care Science, Research Institute, National Center for Geriatrics and Gerontology, Aichi 474-8511, Japan., Tsunekawa S; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan., Yabe D; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan., Iwasaki Y; Laboratory of Animal Functional Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan., Seino Y; Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan., Yada T; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Kobe Biotechnology Research and Human Resource Development Center, Kobe University Graduate School of Medicine, Kobe 650-0047, Japan; Center for One Medicine Innovative Translational Research, Gifu University Institute for Advanced Study, Gifu 501-1194, Japan; Department of Endocrinology, Diabetes and Metabolism, Fujita Health University School of Medicine, Aichi 470-1192, Japan. Electronic address: toshihiko.yada@kepmri.org.
Source: The journal of physiological sciences : JPS [J Physiol Sci] 2026 Mar; Vol. 76 (1), pp. 100062. Date of Electronic Publication: 2026 Jan 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer Japan Country of Publication: United States NLM ID: 101262417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-6562 (Electronic) Linking ISSN: 18806546 NLM ISO Abbreviation: J Physiol Sci Subsets: MEDLINE
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  Data: Circadian feeding promotion by Ninjin'yoeito counteracts frailty in aged mice.
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  Data: <searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Kobe Biotechnology Research and Human Resource Development Center, Kobe University Graduate School of Medicine, Kobe 650-0047, Japan; Division of Health Sciences, Medicine and Aging, Bin Zhou Polytechnic, Binzhou 256-603, China.<br /><searchLink fieldCode="AU" term="%22Rakhat+Y%22">Rakhat Y</searchLink>; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.<br /><searchLink fieldCode="AU" term="%22Nakata+M%22">Nakata M</searchLink>; Department of Physiology, Faculty of Medicine, Wakayama Medical University School of Medicine, Wakayama 641-8509, Japan.<br /><searchLink fieldCode="AU" term="%22Dezaki+K%22">Dezaki K</searchLink>; Faculty of Pharmacy, Iryo Sosei University, Iwaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kuwata+H%22">Kuwata H</searchLink>; Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Department of Physiology, Faculty of Medicine, Wakayama Medical University School of Medicine, Wakayama 641-8509, Japan.<br /><searchLink fieldCode="AU" term="%22Han+W%22">Han W</searchLink>; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Kobe Biotechnology Research and Human Resource Development Center, Kobe University Graduate School of Medicine, Kobe 650-0047, Japan.<br /><searchLink fieldCode="AU" term="%22Banno+S%22">Banno S</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.<br /><searchLink fieldCode="AU" term="%22Abe+C%22">Abe C</searchLink>; Department of Physiology, University of Fukui School of Medical Sciences, Fukui 910-1193, Japan.<br /><searchLink fieldCode="AU" term="%22Ogiso+N%22">Ogiso N</searchLink>; Faculty of Health and Medical Sciences, Aichi Syukutoku University, Nagakute, 480-1197, Japan.<br /><searchLink fieldCode="AU" term="%22Sakurai+T%22">Sakurai T</searchLink>; Department of Prevention and Care Science, Research Institute, National Center for Geriatrics and Gerontology, Aichi 474-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Tsunekawa+S%22">Tsunekawa S</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.<br /><searchLink fieldCode="AU" term="%22Yabe+D%22">Yabe D</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Iwasaki+Y%22">Iwasaki Y</searchLink>; Laboratory of Animal Functional Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Seino+Y%22">Seino Y</searchLink>; Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan.<br /><searchLink fieldCode="AU" term="%22Yada+T%22">Yada T</searchLink>; Division of Integrative Physiology, Kansai Electric Power Medical Research Institute, Osaka 553-0003, Japan; Department of Diabetes, Endocrinology and Metabolism, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan; Kobe Biotechnology Research and Human Resource Development Center, Kobe University Graduate School of Medicine, Kobe 650-0047, Japan; Center for One Medicine Innovative Translational Research, Gifu University Institute for Advanced Study, Gifu 501-1194, Japan; Department of Endocrinology, Diabetes and Metabolism, Fujita Health University School of Medicine, Aichi 470-1192, Japan. Electronic address: toshihiko.yada@kepmri.org.
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  Data: <searchLink fieldCode="JN" term="%22101262417%22">The journal of physiological sciences : JPS</searchLink> [J Physiol Sci] 2026 Mar; Vol. 76 (1), pp. 100062. <i>Date of Electronic Publication: </i>2026 Jan 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Japan%22">Springer Japan </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101262417 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1880-6562 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218806546%22">18806546 </searchLink><i>NLM ISO Abbreviation: </i>J Physiol Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jphyss.2026.100062
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        Text: English
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              Text: 2026 Mar
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