Mutant TDP-43 drives impairments in axonal transport and glycolysis in a mouse stem-cell-derived motor neuron model of amyotrophic lateral sclerosis (ALS).

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Title: Mutant TDP-43 drives impairments in axonal transport and glycolysis in a mouse stem-cell-derived motor neuron model of amyotrophic lateral sclerosis (ALS).
Authors: Carroll E; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford, UK., Scaber J; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford, UK., Pasniceanu IS; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford, UK., Dafinca R; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford, UK., Gordon D; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford, UK., Candalija A; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Talbot K; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. kevin.talbot@ndcn.ox.ac.uk.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Oxford, UK. kevin.talbot@ndcn.ox.ac.uk.
Source: Cell death & disease [Cell Death Dis] 2026 Jan 31; Vol. 17 (1), pp. 193. Date of Electronic Publication: 2026 Jan 31.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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