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Off-target binding of 18F-MK-6240 tau PET imaging demonstrated by high spatial resolution dedicated brain PET scanner.

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Title: Off-target binding of 18F-MK-6240 tau PET imaging demonstrated by high spatial resolution dedicated brain PET scanner.
Authors: Ishii K; Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650 - 0016, Hyogo, Japan. ishii@med.kindai.ac.jp.; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan. ishii@med.kindai.ac.jp.; Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, Sakai, Osaka, Japan. ishii@med.kindai.ac.jp., Yamada T; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan., Hanaoka K; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan., Kaida H; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.; Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, Sakai, Osaka, Japan., Kojita Y; Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650 - 0016, Hyogo, Japan.; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan., Kono A; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan., Ishii K; Team for Neuroimaging Research, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan., Kato T; Department of Radiology, National Center for Geriatrics and Gerontology, Obu, Japan., Nakamura A; Department of Clinical and Experimental Neuroimaging, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.; Department of Biomarker Research, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Source: Annals of nuclear medicine [Ann Nucl Med] 2026 May; Vol. 40 (5), pp. 597-604. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Japan Country of Publication: Japan NLM ID: 8913398 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1864-6433 (Electronic) Linking ISSN: 09147187 NLM ISO Abbreviation: Ann Nucl Med Subsets: MEDLINE; In Process
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  Data: Off-target binding of <superscript>18</superscript>F-MK-6240 tau PET imaging demonstrated by high spatial resolution dedicated brain PET scanner.
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  Data: <searchLink fieldCode="AU" term="%22Ishii+K%22">Ishii K</searchLink>; Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650 - 0016, Hyogo, Japan. ishii@med.kindai.ac.jp.; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan. ishii@med.kindai.ac.jp.; Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, Sakai, Osaka, Japan. ishii@med.kindai.ac.jp.<br /><searchLink fieldCode="AU" term="%22Yamada+T%22">Yamada T</searchLink>; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hanaoka+K%22">Hanaoka K</searchLink>; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kaida+H%22">Kaida H</searchLink>; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.; Institute of Advanced Clinical Medicine, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kojita+Y%22">Kojita Y</searchLink>; Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650 - 0016, Hyogo, Japan.; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kono+A%22">Kono A</searchLink>; Department of Radiology, Kindai University Faculty of Medicine, Sakai, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ishii+K%22">Ishii K</searchLink>; Team for Neuroimaging Research, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+T%22">Kato T</searchLink>; Department of Radiology, National Center for Geriatrics and Gerontology, Obu, Japan.<br /><searchLink fieldCode="AU" term="%22Nakamura+A%22">Nakamura A</searchLink>; Department of Clinical and Experimental Neuroimaging, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.; Department of Biomarker Research, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
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  Data: <searchLink fieldCode="JN" term="%228913398%22">Annals of nuclear medicine</searchLink> [Ann Nucl Med] 2026 May; Vol. 40 (5), pp. 597-604. <i>Date of Electronic Publication: </i>2026 Feb 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Japan%22">Springer Japan </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>8913398 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1864-6433 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209147187%22">09147187 </searchLink><i>NLM ISO Abbreviation: </i>Ann Nucl Med <i>Subsets: </i>MEDLINE; In Process
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        Value: 10.1007/s12149-026-02161-9
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              Text: 2026 May
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