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Long-term effectiveness on glycemic control of insulin compared to combined oral antidiabetic drugs for initial intensive treatment in newly diagnosed type 2 diabetes: A duplicated target trial.

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Title: Long-term effectiveness on glycemic control of insulin compared to combined oral antidiabetic drugs for initial intensive treatment in newly diagnosed type 2 diabetes: A duplicated target trial.
Authors: Kim TH; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea., Hwang Y; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea., Woo S; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea., Lee K; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Regulatory Science, Kyung Hee University, Seoul, South Korea., Son Y; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea., Park S; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea., Kim H; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea., Shin JY; School of Pharmacy, Sungkyunkwan University, Suwon, South Korea., Cho Y; RWE Division, Kakao Healthcare Corp., Seongnam, South Korea., Shin D; RWE Division, Kakao Healthcare Corp., Seongnam, South Korea., Cho D; Department of Neurosurgery, College of Medicine, Ewha Womans University, Seoul, South Korea., Lee KJ; Department of Orthopaedic Surgery, Keimyung University Dongsan Hospital, Daegu, South Korea., Rhee SY; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Endocrinology and Metabolism, Kyung Hee University College of Medicine, Seoul, South Korea., Yon DK; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Regulatory Science, Kyung Hee University, Seoul, South Korea.; Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
Source: Medicine [Medicine (Baltimore)] 2026 Jan 30; Vol. 105 (5), pp. e47235.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kim+TH%22">Kim TH</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+Y%22">Hwang Y</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Woo+S%22">Woo S</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+K%22">Lee K</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Regulatory Science, Kyung Hee University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Son+Y%22">Son Y</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Shin+JY%22">Shin JY</searchLink>; School of Pharmacy, Sungkyunkwan University, Suwon, South Korea.<br /><searchLink fieldCode="AU" term="%22Cho+Y%22">Cho Y</searchLink>; RWE Division, Kakao Healthcare Corp., Seongnam, South Korea.<br /><searchLink fieldCode="AU" term="%22Shin+D%22">Shin D</searchLink>; RWE Division, Kakao Healthcare Corp., Seongnam, South Korea.<br /><searchLink fieldCode="AU" term="%22Cho+D%22">Cho D</searchLink>; Department of Neurosurgery, College of Medicine, Ewha Womans University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KJ%22">Lee KJ</searchLink>; Department of Orthopaedic Surgery, Keimyung University Dongsan Hospital, Daegu, South Korea.<br /><searchLink fieldCode="AU" term="%22Rhee+SY%22">Rhee SY</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Endocrinology and Metabolism, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Yon+DK%22">Yon DK</searchLink>; Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.; Department of Regulatory Science, Kyung Hee University, Seoul, South Korea.; Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
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