Region-resolved proteomic map of the human brain: functional interconnections and neurological implications.

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Title: Region-resolved proteomic map of the human brain: functional interconnections and neurological implications.
Authors: Zhang PP; Chongqing Institute of Advanced Pathology and Yu-Yue Scientific Research Center for Pathology, Jinfeng Laboratory, Chongqing, China.; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.; Department of Pathology, Ruijin Hospital and College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Li MS; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, China., Zhou J; Stem Cell and Regenerative Medicine Lab, National Infrastructures for Translational Medicine and State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Zhu CH; Department of Anatomy, Third Military Medical University (Army Medical University), Chongqing, China., Tang R; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China., He ZC; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China., Yao XH; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.; Jinfeng Laboratory, Chongqing, China., Ping YF; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.; Jinfeng Laboratory, Chongqing, China., Xiang DF; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China., Tan LY; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China., Wang YJ; Stem Cell and Regenerative Medicine Lab, National Infrastructures for Translational Medicine and State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Wang S; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China., Li SS; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China., Ma J; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, China., Zhu YP; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, China. zhuyunping@ncpsb.org.cn., Bian XW; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China. bianxiuwu@tmmu.edu.cn.; Jinfeng Laboratory, Chongqing, China. bianxiuwu@tmmu.edu.cn., Leng L; Stem Cell and Regenerative Medicine Lab, National Infrastructures for Translational Medicine and State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. lengling@pumch.cn.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Feb 04; Vol. 11 (1), pp. 43. Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
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  Data: Region-resolved proteomic map of the human brain: functional interconnections and neurological implications.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+PP%22">Zhang PP</searchLink>; Chongqing Institute of Advanced Pathology and Yu-Yue Scientific Research Center for Pathology, Jinfeng Laboratory, Chongqing, China.; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.; Department of Pathology, Ruijin Hospital and College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+MS%22">Li MS</searchLink>; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Stem Cell and Regenerative Medicine Lab, National Infrastructures for Translational Medicine and State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+CH%22">Zhu CH</searchLink>; Department of Anatomy, Third Military Medical University (Army Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Tang+R%22">Tang R</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22He+ZC%22">He ZC</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Yao+XH%22">Yao XH</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.; Jinfeng Laboratory, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Ping+YF%22">Ping YF</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.; Jinfeng Laboratory, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Xiang+DF%22">Xiang DF</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Tan+LY%22">Tan LY</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wang+YJ%22">Wang YJ</searchLink>; Stem Cell and Regenerative Medicine Lab, National Infrastructures for Translational Medicine and State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Li+SS%22">Li SS</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+YP%22">Zhu YP</searchLink>; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, China. zhuyunping@ncpsb.org.cn.<br /><searchLink fieldCode="AU" term="%22Bian+XW%22">Bian XW</searchLink>; Institute of Pathology, Medical Research Center for Glioma, Southwest Cancer Center, the First Affliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China. bianxiuwu@tmmu.edu.cn.; Jinfeng Laboratory, Chongqing, China. bianxiuwu@tmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Leng+L%22">Leng L</searchLink>; Stem Cell and Regenerative Medicine Lab, National Infrastructures for Translational Medicine and State Key Laboratory for Complex, Severe, and Rare Diseases, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. lengling@pumch.cn.
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