Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway.

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Title: Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway.
Authors: Gu QS; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Gu YF; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Li JQ; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Li YH; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Chen YH; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Wang LH; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Wang ZR; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Wang YC; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China., Yang M; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.
Source: The Kaohsiung journal of medical sciences [Kaohsiung J Med Sci] 2026 Feb 04, pp. e70175. Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Department of Public Health, Kaohsiung Medical University Country of Publication: China (Republic : 1949- ) NLM ID: 100960562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2410-8650 (Electronic) Linking ISSN: 1607551X NLM ISO Abbreviation: Kaohsiung J Med Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway.
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  Data: <searchLink fieldCode="AU" term="%22Gu+QS%22">Gu QS</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gu+YF%22">Gu YF</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+JQ%22">Li JQ</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+YH%22">Li YH</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+LH%22">Wang LH</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+ZR%22">Wang ZR</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+YC%22">Wang YC</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Department of Trauma Orthopedics, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, People's Republic of China.
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  Data: <searchLink fieldCode="JN" term="%22100960562%22">The Kaohsiung journal of medical sciences</searchLink> [Kaohsiung J Med Sci] 2026 Feb 04, pp. e70175. <i>Date of Electronic Publication: </i>2026 Feb 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Department+of+Public+Health%2C+Kaohsiung+Medical+University%22">Department of Public Health, Kaohsiung Medical University </searchLink><i>Country of Publication: </i>China (Republic : 1949- ) <i>NLM ID: </i>100960562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2410-8650 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221607551X%22">1607551X </searchLink><i>NLM ISO Abbreviation: </i>Kaohsiung J Med Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1002/kjm2.70175
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              Text: 2026 Feb 04
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              Y: 2026
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