Luteolin mitigates inflammatory organ injury by targeting XIAP to block PANoptosis and mitochondrial dysfunction.
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| Title: | Luteolin mitigates inflammatory organ injury by targeting XIAP to block PANoptosis and mitochondrial dysfunction. |
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| Authors: | Shi FL; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Postdoctoral Research Station, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Lv YF; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; School of Basic Medical Sciences, Nanchang University, Nanchang 330031, China., Luo SQ; Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Sun YX; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Wen XQ; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; School of Basic Medical Sciences, Nanchang University, Nanchang 330031, China., Ren YX; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Yang YX; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Yu P; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Chen QF; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China; School of Basic Medical Sciences, Nanchang University, Nanchang 330031, China., Yang XH; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Xu S; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Qing J; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China., Ouyang DY; Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Li JM; Key Laboratory of Precision Pathology and Intelligent Diagnosis of Jiangxi Province, Department of Pathology and Molecular Pathology Institute, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Department of Pathology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China; Department of Pathology, Soochow University Medical School, Suzhou 215123, China. Electronic address: jianmingli@ncu.edu.cn. |
| Source: | International immunopharmacology [Int Immunopharmacol] 2026 Mar 15; Vol. 173, pp. 116271. Date of Electronic Publication: 2026 Feb 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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