Tapentadol induces progressive hepatic damage via disrupting Hippo-YAP and bile acid-FXR pathways: An integrated experimental and computational perspective.
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| Title: | Tapentadol induces progressive hepatic damage via disrupting Hippo-YAP and bile acid-FXR pathways: An integrated experimental and computational perspective. |
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| Authors: | Hu H; Department of General Surgery, The Fifth Hospital of Wuhan (The Second Affiliated Hospital of Jianghan University), Wuhan, Hubei, 430050, China. Electronic address: 285507525@qq.com., Jamil S; Department of Pathology, College of Medicine, King Khalid University, P.O. 641, Abha 61421, Saudi Arabia., Azmat MB; International School of Medicine-International University of Kyrgyzstan, Bishkek, Kyrgyzstan. Electronic address: bilalazmat122@gmail.com., Alissa M; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia., Aloraini GS; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia., Albati AA; Biochemistry Department, College of Science, King Saud University, Riyadh 11495, Saudi Arabia., Al-Emam A; Department of Pathology, College of Medicine, King Khalid University, P.O. 641, Abha 61421, Saudi Arabia., Hassan HM; Department of Pathology, College of Medicine, King Khalid University, P.O. 641, Abha 61421, Saudi Arabia. |
| Source: | Tissue & cell [Tissue Cell] 2026 Jun; Vol. 100, pp. 103362. Date of Electronic Publication: 2026 Jan 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41637922 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Tapentadol induces progressive hepatic damage via disrupting Hippo-YAP and bile acid-FXR pathways: An integrated experimental and computational perspective. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hu+H%22">Hu H</searchLink>; Department of General Surgery, The Fifth Hospital of Wuhan (The Second Affiliated Hospital of Jianghan University), Wuhan, Hubei, 430050, China. Electronic address: 285507525@qq.com.<br /><searchLink fieldCode="AU" term="%22Jamil+S%22">Jamil S</searchLink>; Department of Pathology, College of Medicine, King Khalid University, P.O. 641, Abha 61421, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Azmat+MB%22">Azmat MB</searchLink>; International School of Medicine-International University of Kyrgyzstan, Bishkek, Kyrgyzstan. Electronic address: bilalazmat122@gmail.com.<br /><searchLink fieldCode="AU" term="%22Alissa+M%22">Alissa M</searchLink>; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aloraini+GS%22">Aloraini GS</searchLink>; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Albati+AA%22">Albati AA</searchLink>; Biochemistry Department, College of Science, King Saud University, Riyadh 11495, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Emam+A%22">Al-Emam A</searchLink>; Department of Pathology, College of Medicine, King Khalid University, P.O. 641, Abha 61421, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hassan+HM%22">Hassan HM</searchLink>; Department of Pathology, College of Medicine, King Khalid University, P.O. 641, Abha 61421, Saudi Arabia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220214745%22">Tissue & cell</searchLink> [Tissue Cell] 2026 Jun; Vol. 100, pp. 103362. <i>Date of Electronic Publication: </i>2026 Jan 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Churchill+Livingstone%22">Churchill Livingstone </searchLink><i>Country of Publication: </i>Scotland <i>NLM ID: </i>0214745 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-3072 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200408166%22">00408166 </searchLink><i>NLM ISO Abbreviation: </i>Tissue Cell <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41637922 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.tice.2026.103362 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 103362 Titles: – TitleFull: Tapentadol induces progressive hepatic damage via disrupting Hippo-YAP and bile acid-FXR pathways: An integrated experimental and computational perspective. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hu H – PersonEntity: Name: NameFull: Jamil S – PersonEntity: Name: NameFull: Azmat MB – PersonEntity: Name: NameFull: Alissa M – PersonEntity: Name: NameFull: Aloraini GS – PersonEntity: Name: NameFull: Albati AA – PersonEntity: Name: NameFull: Al-Emam A – PersonEntity: Name: NameFull: Hassan HM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1532-3072 Numbering: – Type: volume Value: 100 Titles: – TitleFull: Tissue & cell Type: main |
| ResultId | 1 |
