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Clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases.

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Title: Clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases.
Authors: Lam MT; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Basu A; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio., Brodeur KE; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., LeSon CE; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Hsu EE; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Alhezam MA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Weng R; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Okada S; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Rimland CA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, Mass., Yue J; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Department of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, China., Peng XP; Division of Pediatric Genetic Medicine, Department of Pediatrics, Children's Hospital at Montefiore, Bronx, NY., Wysocki C; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Tex., Ramanathan A; Kaiser Permanente School of Medicine, Los Angeles, Calif., Huang Z; Department of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, China., Andzelm MM; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Jiang CL; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Wobma H; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Chang JC; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Chou J; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Son MBF; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Platt CD; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Henderson LA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass., Abraham RS; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio. Electronic address: Roshini.Abraham@nationwidechildrens.org., Lee PY; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: Pui.lee@childrens.harvard.edu.
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 Jun; Vol. 157 (6), pp. 1411-1422.e12. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases.
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  Data: <searchLink fieldCode="AU" term="%22Lam+MT%22">Lam MT</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Basu+A%22">Basu A</searchLink>; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Brodeur+KE%22">Brodeur KE</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22LeSon+CE%22">LeSon CE</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Hsu+EE%22">Hsu EE</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Alhezam+MA%22">Alhezam MA</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Weng+R%22">Weng R</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Okada+S%22">Okada S</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Rimland+CA%22">Rimland CA</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Yue+J%22">Yue J</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Department of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Peng+XP%22">Peng XP</searchLink>; Division of Pediatric Genetic Medicine, Department of Pediatrics, Children's Hospital at Montefiore, Bronx, NY.<br /><searchLink fieldCode="AU" term="%22Wysocki+C%22">Wysocki C</searchLink>; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Tex.<br /><searchLink fieldCode="AU" term="%22Ramanathan+A%22">Ramanathan A</searchLink>; Kaiser Permanente School of Medicine, Los Angeles, Calif.<br /><searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; Department of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Andzelm+MM%22">Andzelm MM</searchLink>; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Jiang+CL%22">Jiang CL</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Wobma+H%22">Wobma H</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Chang+JC%22">Chang JC</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Chou+J%22">Chou J</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Son+MBF%22">Son MBF</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Platt+CD%22">Platt CD</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Henderson+LA%22">Henderson LA</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.<br /><searchLink fieldCode="AU" term="%22Abraham+RS%22">Abraham RS</searchLink>; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio. Electronic address: Roshini.Abraham@nationwidechildrens.org.<br /><searchLink fieldCode="AU" term="%22Lee+PY%22">Lee PY</searchLink>; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: Pui.lee@childrens.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2026 Jun; Vol. 157 (6), pp. 1411-1422.e12. <i>Date of Electronic Publication: </i>2026 Feb 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1275002 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200916749%22">00916749 </searchLink><i>NLM ISO Abbreviation: </i>J Allergy Clin Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jaci.2026.01.021
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