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Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC).

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Title: Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC).
Authors: Liao W; Division of Cardiovascular Sciences, School of Medical Sciences, University of Leicester, Leicester, UK. Electronic address: weiqi.liao@leicester.ac.uk., Rashid M; Division of Cardiovascular Sciences, School of Medical Sciences, University of Leicester, Leicester, UK., Brookes CL; Leicester Clinical Trials Unit, University of Leicester, Leicester, UK., Barber S; Leicester Clinical Trials Unit, University of Leicester, Leicester, UK., Turner RM; Medical Research Council Clinical Trials Unit at UCL, UK., Gravel GM; Montreal Heart Institute, Université de Montréal, Montréal, Quebec, Canada., Petrie MC; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK., Lipsic E; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Doenst T; Jena University Hospital, Friedrich-Schiller-University of Jena, Jena, Germany., Fremes S; Department of Surgery, University of Toronto for Fremes,Toronto, Canada., Murphy GJ; Division of Cardiovascular Sciences, School of Medical Sciences, University of Leicester, Leicester, UK; Leicester Clinical Trials Unit, University of Leicester, Leicester, UK.
Corporate Authors: High-Risk REVASC consortium
Source: American heart journal [Am Heart J] 2026 Jun; Vol. 296, pp. 107368. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC).
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  Data: <searchLink fieldCode="AU" term="%22Liao+W%22">Liao W</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, University of Leicester, Leicester, UK. Electronic address: weiqi.liao@leicester.ac.uk.<br /><searchLink fieldCode="AU" term="%22Rashid+M%22">Rashid M</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Brookes+CL%22">Brookes CL</searchLink>; Leicester Clinical Trials Unit, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Barber+S%22">Barber S</searchLink>; Leicester Clinical Trials Unit, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Turner+RM%22">Turner RM</searchLink>; Medical Research Council Clinical Trials Unit at UCL, UK.<br /><searchLink fieldCode="AU" term="%22Gravel+GM%22">Gravel GM</searchLink>; Montreal Heart Institute, Université de Montréal, Montréal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Petrie+MC%22">Petrie MC</searchLink>; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Lipsic+E%22">Lipsic E</searchLink>; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Doenst+T%22">Doenst T</searchLink>; Jena University Hospital, Friedrich-Schiller-University of Jena, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Fremes+S%22">Fremes S</searchLink>; Department of Surgery, University of Toronto for Fremes,Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Murphy+GJ%22">Murphy GJ</searchLink>; Division of Cardiovascular Sciences, School of Medical Sciences, University of Leicester, Leicester, UK; Leicester Clinical Trials Unit, University of Leicester, Leicester, UK.
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  Data: <searchLink fieldCode="CA" term="%22High-Risk+REVASC+consortium%22">High-Risk REVASC consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220370465%22">American heart journal</searchLink> [Am Heart J] 2026 Jun; Vol. 296, pp. 107368. <i>Date of Electronic Publication: </i>2026 Feb 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370465 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200028703%22">00028703 </searchLink><i>NLM ISO Abbreviation: </i>Am Heart J <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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