Comprehensive evaluation of the anti-inflammatory potential of Cucurbita maxima leaf extract: LC-MS phytochemical profiling coupled with in vitro, in vivo, and in silico approaches.

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Title: Comprehensive evaluation of the anti-inflammatory potential of Cucurbita maxima leaf extract: LC-MS phytochemical profiling coupled with in vitro, in vivo, and in silico approaches.
Authors: Maroua H; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: hammadi-maroua@univ-eloued.dz., Larbi Benamor M; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: benamor-mohmmedlarbi@univ-eloued.dz., Bekkar Y; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria., Neghmouche Nacer S; Department of Chemistry, Faculty of Exact Sciences, University of El Oued, P.O. Box 789, El Oued, 39000, Algeria. Electronic address: neghmouchenacer-salah@univ-eloued.dz., Lanez E; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: lanez-elhafnaoui@univ-eloued.dz., Boudebia O; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: boudebia-ouafa@univ-eloued.dz., Chaoua H; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: housseyn-chaoua@univ-eloued.dz., Adaika A; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: adaikaicha@gmail.com., Bechki L; Kasdi Merbah University, VPRS Laboratory, Department of Chemistry, Faculty of Mathematics and Material Sciences, 30000, Ouargla, Algeria. Electronic address: lbechki1@gmail.com., Lanez T; University of El Oued, Faculty of Exact Sciences, Department of Chemistry, VTRS Laboratory, B.P.789, 39000, El Oued, Algeria. Electronic address: touhami-lanez@univ-eloued.dz., Garzoli S; Department of Chemistry and Technologies of Drug, Sapienza University, P. le Aldo Moro, 5, 00185, Rome, Italy. Electronic address: stefania.garzoli@uniroma1.it.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 May 10; Vol. 362, pp. 121267. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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