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Atlas-guided discovery of transcription factors for T cell programming.

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Title: Atlas-guided discovery of transcription factors for T cell programming.
Authors: Chung HK; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA. hkchung@unc.edu.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. hkchung@unc.edu.; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. hkchung@unc.edu., Liu C; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Battu A; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jambor AN; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA., Pratt BM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Xie F; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Riesenberg BP; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Casillas E; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Sun M; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Landoni E; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Li Y; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ye Q; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Joo D; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Green J; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Syed Z; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Brown NJ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Smith M; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ma S; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Tan S; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Chick B; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA., Tripple V; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Wang ZA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Wang J; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Mcdonald B; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., He P; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.; Department of Bioengineering, Institute of Engineering in Medicine, University of California, La Jolla, CA, USA., Yang Q; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Chen T; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Varanasi SK; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., LaPorta MA; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Mann TH; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Chen D; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Hoffmann F; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA., Ho J; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA., Modliszewski J; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Williams A; Razavi Newman Integrative Genomics and Bioinformatics Core, Salk Institute for Biological Studies, La Jolla, CA, USA., Liu Y; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wang Z; Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, CA, USA., Liu J; Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, CA, USA., Gao Y; Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA., Hu Z; Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, CA, USA., Cho UH; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Liu L; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Wang Y; Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA., Hargreaves DC; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA., Dotti G; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Savoldo B; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Thaxton JE; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Milner JJ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Kaech SM; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA. sue.kaech@alleninstitute.org.; Institute for Immunology, Allen Institute, Seattle, WA, USA. sue.kaech@alleninstitute.org., Wang W; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA. wei-wang@ucsd.edu.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA. wei-wang@ucsd.edu.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. wei-wang@ucsd.edu.
Source: Nature [Nature] 2026 Mar; Vol. 651 (8107), pp. 1077-1087. Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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              Value: 651
            – Type: issue
              Value: 8107
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1