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Targeting spinal cord perfusion pressure in acute spinal cord injury through cerebrospinal fluid drainage: A prospective multi-center clinical trial.

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Title: Targeting spinal cord perfusion pressure in acute spinal cord injury through cerebrospinal fluid drainage: A prospective multi-center clinical trial.
Authors: Gee CM; International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Tsang A; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada., McKenzie M; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada., Belanger L; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada., Ritchie L; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada., Ailon T; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Dandurand C; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Paquette S; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Charest-Morin R; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Dea N; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Street J; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Fisher CG; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Wilson J; Department of Neurosurgery, University of Toronto, Toronto, Ontario, Canada., DiGiorgio A; Department of Neurological Surgery, University of California San Francisco (UCSF), San Francisco, California, United States of America., Mac-Thiong JM; Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada., Christie S; Division of Neurosurgery, Dalhousie University, Halifax, Nova Scotia, Canada., Wilson J; Department of Neurosurgery, University of Nebraska, Lincoln, Nebraska, United States of America.; Medical University of South Carolina, Charleston, South Carolina, United States of America., Ricks C; Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico, United States of America., Okonkwo D; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Kwon BK; International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Source: PLoS medicine [PLoS Med] 2026 Feb 05; Vol. 23 (2), pp. e1004925. Date of Electronic Publication: 2026 Feb 05 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study; Clinical Trial
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet ISSN: 1549-1676 (Electronic) Linking ISSN: 15491277 NLM ISO Abbreviation: PLoS Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting spinal cord perfusion pressure in acute spinal cord injury through cerebrospinal fluid drainage: A prospective multi-center clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Gee+CM%22">Gee CM</searchLink>; International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Tsang+A%22">Tsang A</searchLink>; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22McKenzie+M%22">McKenzie M</searchLink>; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Belanger+L%22">Belanger L</searchLink>; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Ritchie+L%22">Ritchie L</searchLink>; Vancouver Spine Research Program, Vancouver General Hospital, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Ailon+T%22">Ailon T</searchLink>; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Dandurand+C%22">Dandurand C</searchLink>; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Paquette+S%22">Paquette S</searchLink>; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Charest-Morin+R%22">Charest-Morin R</searchLink>; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Dea+N%22">Dea N</searchLink>; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Street+J%22">Street J</searchLink>; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Fisher+CG%22">Fisher CG</searchLink>; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+J%22">Wilson J</searchLink>; Department of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22DiGiorgio+A%22">DiGiorgio A</searchLink>; Department of Neurological Surgery, University of California San Francisco (UCSF), San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Mac-Thiong+JM%22">Mac-Thiong JM</searchLink>; Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Christie+S%22">Christie S</searchLink>; Division of Neurosurgery, Dalhousie University, Halifax, Nova Scotia, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+J%22">Wilson J</searchLink>; Department of Neurosurgery, University of Nebraska, Lincoln, Nebraska, United States of America.; Medical University of South Carolina, Charleston, South Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Ricks+C%22">Ricks C</searchLink>; Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico, United States of America.<br /><searchLink fieldCode="AU" term="%22Okonkwo+D%22">Okonkwo D</searchLink>; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Kwon+BK%22">Kwon BK</searchLink>; International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101231360%22">PLoS medicine</searchLink> [PLoS Med] 2026 Feb 05; Vol. 23 (2), pp. e1004925. <i>Date of Electronic Publication: </i>2026 Feb 05 (<i>Print Publication: </i>2026).
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