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Sclerostin deficiency sensitizes white adipocytes to thermogenic signals that induce beiging in mice.

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Title: Sclerostin deficiency sensitizes white adipocytes to thermogenic signals that induce beiging in mice.
Authors: Choquette GM; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA., Kim SP; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Wilkinson KJ; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA., Avelar BC; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA., Pathy S; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA., Li Z; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA., Wu J; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA., Aja S; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Thorek DLJ; Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.; Department of Biomedical Engineering, Washington University in St. Louis School of Medicine, Baltimore, MD, USA.; Siteman Cancer Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Wolfgang MJ; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Riddle RC; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA. rriddle@som.umaryland.edu.; Research and Development Service, Baltimore VA Medical Center, Baltimore, MD, USA. rriddle@som.umaryland.edu.
Source: Nature communications [Nat Commun] 2026 Feb 05; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Choquette+GM%22">Choquette GM</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kim+SP%22">Kim SP</searchLink>; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wilkinson+KJ%22">Wilkinson KJ</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Avelar+BC%22">Avelar BC</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pathy+S%22">Pathy S</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Aja+S%22">Aja S</searchLink>; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Thorek+DLJ%22">Thorek DLJ</searchLink>; Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.; Department of Biomedical Engineering, Washington University in St. Louis School of Medicine, Baltimore, MD, USA.; Siteman Cancer Center, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Wolfgang+MJ%22">Wolfgang MJ</searchLink>; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Riddle+RC%22">Riddle RC</searchLink>; Division of Musculoskeletal Sciences, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA. rriddle@som.umaryland.edu.; Research and Development Service, Baltimore VA Medical Center, Baltimore, MD, USA. rriddle@som.umaryland.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Feb 05; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 05.
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              Text: 2026 Feb 05
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