Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation.
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| Title: | Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation. |
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| Authors: | Fisher IJ; James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA., Senarath K; Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, USA., Outlaw K; James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA., Muralidharan K; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.; Center for Clinical and Translational Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Garland-Kuntz EE; James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA., Van Camp M; James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA., Komay T; James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan.; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan., Kostenis E; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Lambert NA; Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, USA., Lyon AM; James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 14. Date of Electronic Publication: 2026 Jan 14. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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