A Comparison of F/TAF and F/TDF as HIV Pre-Exposure Prophylaxis in a Predominantly Cisgender Women Population in East and South Africa: A Randomized, Factorial, Noninferiority Trial.
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| Title: | A Comparison of F/TAF and F/TDF as HIV Pre-Exposure Prophylaxis in a Predominantly Cisgender Women Population in East and South Africa: A Randomized, Factorial, Noninferiority Trial. |
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| Authors: | McCormack S; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom., Dunn D; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom., Kusemererwa S; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Munseri P; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Singh N; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., William W; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania., Mutonyi G; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Bern H; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom., Goldwirt L; Université de Paris Hôpital Saint-Louis Laboratoire de Pharmacologie Biologique, Paris, France., Kingsley C; Imperial College of Science, Technology and Medicine, London, United Kingdom., Kroidl A; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany., Hansen CH; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Ding S; EuroVacc Foundation, Lausanne, Switzerland., Kawuma R; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Amondi M; International AIDS Vaccine Initiative, New York, USA., Bahemuka U; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Buma D; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Clutterbuck D; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom., Gaffoor Z; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., Jennings A; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom., Joachim A; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Kakande A; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Kalanzi B; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Kisinda A; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania., Matsoso M; EuroVacc Foundation, Lausanne, Switzerland., Miller T; Imperial College of Science, Technology and Medicine, London, United Kingdom., Morar N; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., Musau J; International AIDS Vaccine Initiative, New York, USA., Nabbuto J; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Nzuza A; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., Pamba D; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania., Salomone S; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom., Sithole T; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., Tarimo E; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Woeber K; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., Chinyenze K; International AIDS Vaccine Initiative, New York, USA., Gray G; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa., Lyamuya E; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Bakari M; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Aboud S; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania., Maganga L; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania., Doncel G; CONRAD, Eastern Virginia Medical School, Old Dominion University, Norfolk, United Kingdom; and., Seeley J; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Weber J; Imperial College of Science, Technology and Medicine, London, United Kingdom.; Institute of Health, University of Cumbria, Carlisle, United Kingdom., Kaleebu P; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda., Fox J; Imperial College of Science, Technology and Medicine, London, United Kingdom., Ruzagira E; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda. |
| Corporate Authors: | PrEPVacc Study Group |
| Source: | Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2026 Jun 01; Vol. 101 (6), pp. 655-662. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Equivalence Trial; Comparative Study; Multicenter Study |
| Journal Info: | Publisher: Lippincott Williams & Wilkins, Inc Country of Publication: United States NLM ID: 100892005 Publication Model: Print Cited Medium: Internet ISSN: 1944-7884 (Electronic) Linking ISSN: 15254135 NLM ISO Abbreviation: J Acquir Immune Defic Syndr Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41650395 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Comparison of F/TAF and F/TDF as HIV Pre-Exposure Prophylaxis in a Predominantly Cisgender Women Population in East and South Africa: A Randomized, Factorial, Noninferiority Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22McCormack+S%22">McCormack S</searchLink>; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dunn+D%22">Dunn D</searchLink>; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kusemererwa+S%22">Kusemererwa S</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Munseri+P%22">Munseri P</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Singh+N%22">Singh N</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22William+W%22">William W</searchLink>; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Mutonyi+G%22">Mutonyi G</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Bern+H%22">Bern H</searchLink>; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goldwirt+L%22">Goldwirt L</searchLink>; Université de Paris Hôpital Saint-Louis Laboratoire de Pharmacologie Biologique, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kingsley+C%22">Kingsley C</searchLink>; Imperial College of Science, Technology and Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kroidl+A%22">Kroidl A</searchLink>; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hansen+CH%22">Hansen CH</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Ding+S%22">Ding S</searchLink>; EuroVacc Foundation, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kawuma+R%22">Kawuma R</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Amondi+M%22">Amondi M</searchLink>; International AIDS Vaccine Initiative, New York, USA.<br /><searchLink fieldCode="AU" term="%22Bahemuka+U%22">Bahemuka U</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Buma+D%22">Buma D</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Clutterbuck+D%22">Clutterbuck D</searchLink>; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gaffoor+Z%22">Gaffoor Z</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Jennings+A%22">Jennings A</searchLink>; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Joachim+A%22">Joachim A</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Kakande+A%22">Kakande A</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kalanzi+B%22">Kalanzi B</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kisinda+A%22">Kisinda A</searchLink>; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Matsoso+M%22">Matsoso M</searchLink>; EuroVacc Foundation, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Miller+T%22">Miller T</searchLink>; Imperial College of Science, Technology and Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Morar+N%22">Morar N</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Musau+J%22">Musau J</searchLink>; International AIDS Vaccine Initiative, New York, USA.<br /><searchLink fieldCode="AU" term="%22Nabbuto+J%22">Nabbuto J</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Nzuza+A%22">Nzuza A</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Pamba+D%22">Pamba D</searchLink>; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Salomone+S%22">Salomone S</searchLink>; Medical Research Council Clinical Trials Unit at UCL, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sithole+T%22">Sithole T</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Tarimo+E%22">Tarimo E</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Woeber+K%22">Woeber K</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Chinyenze+K%22">Chinyenze K</searchLink>; International AIDS Vaccine Initiative, New York, USA.<br /><searchLink fieldCode="AU" term="%22Gray+G%22">Gray G</searchLink>; South African Medical Research Council, HIV and other Infectious Diseases Research Unit, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Lyamuya+E%22">Lyamuya E</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Bakari+M%22">Bakari M</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Aboud+S%22">Aboud S</searchLink>; Muhimbili University Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Maganga+L%22">Maganga L</searchLink>; National Institute for Medical Research Mbeya Medical Research Centre, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Doncel+G%22">Doncel G</searchLink>; CONRAD, Eastern Virginia Medical School, Old Dominion University, Norfolk, United Kingdom; and.<br /><searchLink fieldCode="AU" term="%22Seeley+J%22">Seeley J</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Weber+J%22">Weber J</searchLink>; Imperial College of Science, Technology and Medicine, London, United Kingdom.; Institute of Health, University of Cumbria, Carlisle, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kaleebu+P%22">Kaleebu P</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Fox+J%22">Fox J</searchLink>; Imperial College of Science, Technology and Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ruzagira+E%22">Ruzagira E</searchLink>; Medical Research Council/Uganda Virus Research Institute & London School of Hygiene & Tropical Medicine Uganda Unit, Entebbe, Uganda. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22PrEPVacc+Study+Group%22">PrEPVacc Study Group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100892005%22">Journal of acquired immune deficiency syndromes (1999)</searchLink> [J Acquir Immune Defic Syndr] 2026 Jun 01; Vol. 101 (6), pp. 655-662. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Equivalence Trial; Comparative Study; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%2C+Inc%22">Lippincott Williams & Wilkins, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100892005 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1944-7884 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215254135%22">15254135 </searchLink><i>NLM ISO Abbreviation: </i>J Acquir Immune Defic Syndr <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1097/QAI.0000000000003845 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 655 Titles: – TitleFull: A Comparison of F/TAF and F/TDF as HIV Pre-Exposure Prophylaxis in a Predominantly Cisgender Women Population in East and South Africa: A Randomized, Factorial, Noninferiority Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: McCormack S – PersonEntity: Name: NameFull: Dunn D – PersonEntity: Name: NameFull: Kusemererwa S – PersonEntity: Name: NameFull: Munseri P – PersonEntity: Name: NameFull: Singh N – PersonEntity: Name: NameFull: William W – PersonEntity: Name: NameFull: Mutonyi G – PersonEntity: Name: NameFull: Bern H – PersonEntity: Name: NameFull: Goldwirt L – PersonEntity: Name: NameFull: Kingsley C – PersonEntity: Name: NameFull: Kroidl A – PersonEntity: Name: NameFull: Hansen CH – PersonEntity: Name: NameFull: Ding S – PersonEntity: Name: NameFull: Kawuma R – PersonEntity: Name: NameFull: Amondi M – PersonEntity: Name: NameFull: Bahemuka U – PersonEntity: Name: NameFull: Buma D – PersonEntity: Name: NameFull: Clutterbuck D – PersonEntity: Name: NameFull: Gaffoor Z – PersonEntity: Name: NameFull: Jennings A – PersonEntity: Name: NameFull: Joachim A – PersonEntity: Name: NameFull: Kakande A – PersonEntity: Name: NameFull: Kalanzi B – PersonEntity: Name: NameFull: Kisinda A – PersonEntity: Name: NameFull: Matsoso M – PersonEntity: Name: NameFull: Miller T – PersonEntity: Name: NameFull: Morar N – PersonEntity: Name: NameFull: Musau J – PersonEntity: Name: NameFull: Nabbuto J – PersonEntity: Name: NameFull: Nzuza A – PersonEntity: Name: NameFull: Pamba D – PersonEntity: Name: NameFull: Salomone S – PersonEntity: Name: NameFull: Sithole T – PersonEntity: Name: NameFull: Tarimo E – PersonEntity: Name: NameFull: Woeber K – PersonEntity: Name: NameFull: Chinyenze K – PersonEntity: Name: NameFull: Gray G – PersonEntity: Name: NameFull: Lyamuya E – PersonEntity: Name: NameFull: Bakari M – PersonEntity: Name: NameFull: Aboud S – PersonEntity: Name: NameFull: Maganga L – PersonEntity: Name: NameFull: Doncel G – PersonEntity: Name: NameFull: Seeley J – PersonEntity: Name: NameFull: Weber J – PersonEntity: Name: NameFull: Kaleebu P – PersonEntity: Name: NameFull: Fox J – PersonEntity: Name: NameFull: Ruzagira E IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1944-7884 Numbering: – Type: volume Value: 101 – Type: issue Value: 6 Titles: – TitleFull: Journal of acquired immune deficiency syndromes (1999) Type: main |
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