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Inadequate ovarian function suppression and endocrine therapy manipulations in premenopausal patients with early breast cancer on adjuvant LHRH agonist and aromatase inhibitor: a cohort study.

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Title: Inadequate ovarian function suppression and endocrine therapy manipulations in premenopausal patients with early breast cancer on adjuvant LHRH agonist and aromatase inhibitor: a cohort study.
Authors: Valenza C; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Etessami JD; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Milano M; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy., Papadopoulos N; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Alvino M; Division of Pharmacy, European Institute of Oncology, IRCCS, Milan, Italy., Antonarelli G; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Bianco N; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy., Sangalli C; Clinical Trial Office, European Institute of Oncology, IRCCS, Milan, Italy., Trapani D; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Pravettoni G; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, IRCCS, Milan, Italy., Omodeo Salè E; Division of Pharmacy, European Institute of Oncology, IRCCS, Milan, Italy., Passerini R; Division of Laboratory Medicine, European Institute of Oncology, IRCCS, Milan, Italy., Colleoni M; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy., Munzone E; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy., Curigliano G; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. Electronic address: giuseppe.curigliano@ieo.it.
Source: ESMO open [ESMO Open] 2026 Feb; Vol. 11 (2), pp. 106079. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101690685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7029 (Electronic) Linking ISSN: 20597029 NLM ISO Abbreviation: ESMO Open Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Inadequate ovarian function suppression and endocrine therapy manipulations in premenopausal patients with early breast cancer on adjuvant LHRH agonist and aromatase inhibitor: a cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Valenza+C%22">Valenza C</searchLink>; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Etessami+JD%22">Etessami JD</searchLink>; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Milano+M%22">Milano M</searchLink>; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+N%22">Papadopoulos N</searchLink>; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Alvino+M%22">Alvino M</searchLink>; Division of Pharmacy, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Antonarelli+G%22">Antonarelli G</searchLink>; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bianco+N%22">Bianco N</searchLink>; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sangalli+C%22">Sangalli C</searchLink>; Clinical Trial Office, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Trapani+D%22">Trapani D</searchLink>; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pravettoni+G%22">Pravettoni G</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Omodeo+Salè+E%22">Omodeo Salè E</searchLink>; Division of Pharmacy, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Passerini+R%22">Passerini R</searchLink>; Division of Laboratory Medicine, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Colleoni+M%22">Colleoni M</searchLink>; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Munzone+E%22">Munzone E</searchLink>; Division of Medical Senology, European Institute of Oncology, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Curigliano+G%22">Curigliano G</searchLink>; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. Electronic address: giuseppe.curigliano@ieo.it.
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              Text: 2026 Feb
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