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Low shear stress promotes atherosclerosis by inducing endothelial ferroptosis via the P53/xCT pathway.

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Title: Low shear stress promotes atherosclerosis by inducing endothelial ferroptosis via the P53/xCT pathway.
Authors: Hu JW; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Chen YP; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Chen AQ; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Tang JQ; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Tang HY; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Zhang H; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Lu W; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Zhao JY; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Gao XF; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China., Kong XQ; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China. Electronic address: kongdylan@126.com., Zhang JJ; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China. Electronic address: jameszll@163.com.
Source: Experimental cell research [Exp Cell Res] 2026 Apr 01; Vol. 457 (1), pp. 114901. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2422 (Electronic) Linking ISSN: 00144827 NLM ISO Abbreviation: Exp Cell Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Low shear stress promotes atherosclerosis by inducing endothelial ferroptosis via the P53/xCT pathway.
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  Data: <searchLink fieldCode="AU" term="%22Hu+JW%22">Hu JW</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Chen+YP%22">Chen YP</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Chen+AQ%22">Chen AQ</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Tang+JQ%22">Tang JQ</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Tang+HY%22">Tang HY</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Lu+W%22">Lu W</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Zhao+JY%22">Zhao JY</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Gao+XF%22">Gao XF</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China.<br /><searchLink fieldCode="AU" term="%22Kong+XQ%22">Kong XQ</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China. Electronic address: kongdylan@126.com.<br /><searchLink fieldCode="AU" term="%22Zhang+JJ%22">Zhang JJ</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing, 210006, China. Electronic address: jameszll@163.com.
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  Data: <searchLink fieldCode="JN" term="%220373226%22">Experimental cell research</searchLink> [Exp Cell Res] 2026 Apr 01; Vol. 457 (1), pp. 114901. <i>Date of Electronic Publication: </i>2026 Feb 05.
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        Value: 10.1016/j.yexcr.2026.114901
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      – TitleFull: Low shear stress promotes atherosclerosis by inducing endothelial ferroptosis via the P53/xCT pathway.
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              Text: 2026 Apr 01
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